2-Chloro-2,2-difluoro-1-(2,4,5-trimethylphenyl)ethan-1-one CAS 1352226-10-8
| CAS No. | 1352226-10-8 |
| Molecular Formula | C11H11ClF2O |
| Molecular Weight | 232.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-2,2-difluoro-1-(2,4,5-trimethylphenyl)ethan-1-one.
2-Chloro-2,2-difluoro-1-(2,4,5-trimethylphenyl)ethan-1-one (CAS 1352226-10-8), molecular formula C11H11ClF2O and molecular weight 232.65 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C11H11ClF2O, 2-Chloro-2,2-difluoro-1-(2,4,5-trimethylphenyl)ethan-1-one contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 232.65 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H11ClF2O |
| Molecular Weight | 232.65 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
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Recommended Standards
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- 4-[(2,5-Dichlorophenyl)methyl]piperidine (CAS 286469-96-3)
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- 2-Amino-6-bromoquinazoline (CAS 190273-89-3)
- Atorvastatin Cyclic Fluorophenyl Impurity(Potassium Salt) (CAS CATO-C4X-1132116)
- Semaglutide Impurity 183 (CAS 159541-28-3)
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