Methyl 3-amino-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylate CAS 1352400-99-7
| CAS No. | 1352400-99-7 |
| Molecular Formula | C10H9ClN4O2 |
| Molecular Weight | 252.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Methyl 3-amino-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 252.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Methyl 3-amino-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylate (CAS 1352400-99-7), a certified reference material (molecular formula C10H9ClN4O2, MW 252.66 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 3-amino-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9ClN4O2 |
| Molecular Weight | 252.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
- N-(tert-Butyl)-3-chloro-5-(trifluoromethyl)-2-pyridinamine (CAS 1220037-10-4)
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- N-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N,N-diethylamine (CAS 1220029-21-9)
- 4-Chloro-1-methoxy-2-(1,1,1-trifluoro-2-methylpropan-2-yl)benzene (CAS 1402004-24-3)
- 3-(sec-Butyl)-2-ethylpyrazolo[1,5-a]pyridine (CAS 605673-30-1)
- (S)-Dibenzyl 2-aminopentanedioate (CAS 2768-50-5)
- 3-Isopropoxybenzamide (CAS 350989-53-6)
- N-(4-Amino-5-cyclopropoxypyridin-3-yl)methanesulfonamide (CAS 1243350-01-7)
- 2,2',7,7'-Tetra(pyridin-4-yl)-9,9'-spirobi[fluorene] (CAS 1195403-94-1)
- tert-Butyl(S)-(1-oxo-1-(pyrrolidin-1-yl)propan-2-yl)carbamate (CAS 138356-92-0)
- 5-Methoxy-7-methyl-1H-indazole-3-carboxylic acid (CAS 1000340-57-7)
- 5-Hydroxy-3-(trifluoromethyl)picolinamide (CAS 1803855-14-2)
- N1-(3-Acetamidophenyl)-N2-cycloheptyloxalamide (CAS 899748-53-9)
- Neuropeptide Y (22-36) (CAS 119019-65-7)
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