5-Chloro-4-(diethylamino)pyridine-3-sulfonamide CAS 1352498-33-9
| CAS No. | 1352498-33-9 |
| Molecular Formula | C9H14ClN3O2S |
| Molecular Weight | 263.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-4-(diethylamino)pyridine-3-sulfonamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Chloro-4-(diethylamino)pyridine-3-sulfonamide (CAS 1352498-33-9), molecular formula C9H14ClN3O2S and molecular weight 263.74 g/mol, is a CATO reference standard with documented purity and traceability.
5-Chloro-4-(diethylamino)pyridine-3-sulfonamide (C9H14ClN3O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Chloro-4-(diethylamino)pyridine-3-sulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H14ClN3O2S |
| Molecular Weight | 263.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 5-Chloro-n-cyclopentyl-1-methyl-1h-imidazole-4-sulfonamide (CAS 1154914-95-0)
- 1-Chloro-n-(4-methoxybenzyl)-n-methylmethanesulfonamide (CAS 1342992-78-2)
- 5-Chloro-N-ethyl-N-methyl-4-(methylamino)pyridine-3-sulfonamide (CAS 1352515-10-6)
- 2-Chloro-7-methoxy-10H-phenothiazine (CAS 1730-44-5)
- 2-{[6-chloro-2-(methylsulfanyl)pyrimidin-4-yl](2-hydroxyethyl)amino}ethan-1-ol (CAS 339017-88-8)
- 3-Chloro-n-(3-methoxypropyl)benzene-1-sulfonamide (CAS 790263-28-4)
- 4-Chloro-3-methoxy-n-propylbenzenesulfonamide (CAS 898649-86-0)
- 4-Chloro-N-(2-hydroxy-1,1-dimethylethyl)benzenesulfonamide (CAS 59724-57-1)
Recommended Standards
- 4-Amino-5-chloro-N,N-diethylpyridine-3-sulfonamide (CAS 1352485-78-9)
- 3-(4-Chlorophenyl)-3-(4-fluorophenyl)propan-1-amine (CAS 144477-78-1)
- 5-(Pyridin-3-yloxy)pentane-1-sulfonyl chloride (CAS 1341670-53-8)
- 2-(4-chlorophenyl)-4,5,6,7-tetrahydro-1,3-benzothiazol-7-one (CAS 1258650-40-6)
- 1-Tosyl-1H-pyrrolo[3,2-c]pyridine (CAS 1279863-30-7)
- N-[3-(1H-Imidazol-1-yl)propyl]-4-(2-methylbenzoyl)-1H-pyrrole-2-carboxamide (CAS 478249-38-6)
- 4-Iodo-2-(trifluoromethoxy)benzonitrile (CAS 1807054-38-1)
- 4'-Heptyl-[1,1'-biphenyl]-4-carbaldehyde (CAS 93972-08-8)
- Ethyl 2,2-difluoro-2-(pyrimidin-2-yl)acetate (CAS 294181-98-9)
- Olaparib impurity 142 (CAS CATO-C4X-1135142)
- Bis(1H-benzo[d]imidazol-5-yl)methanone (CAS 102342-74-5)
- 4-(2-Chlorophenyl)pyrimidin-2-amine (CAS 874766-80-0)
- (5R,6S)-5,6-Diphenylmorpholin-2-one (CAS 815582-48-0)
- Liraglutide(13-31)TFA Salt (CAS CATO-C4X-19929)
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