3-(1-Methylpiperidin-2-yl)pyridin-2(1H)-one CAS 1352515-58-2
| CAS No. | 1352515-58-2 |
| Molecular Formula | C11H16N2O |
| Molecular Weight | 192.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(1-Methylpiperidin-2-yl)pyridin-2(1H)-one (CAS 1352515-58-2) is a high-purity analytical reference standard with the molecular formula C11H16N2O and a molecular weight of 192.26 g/mol.
3-(1-Methylpiperidin-2-yl)pyridin-2(1H)-one (C11H16N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H16N2O |
| Molecular Weight | 192.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
Related Methylpiperidin Standards
- 2-(2-Methylpiperidin-1-yl)pyrimidin-5-amine (CAS 1249563-11-8)
- 5-(1-Methylpiperidin-2-yl)pyridin-2-ol (CAS 1306605-61-7)
- 6-(4-Methylpiperidin-1-yl)pyrimidin-4-amine (CAS 1314355-53-7)
- 3-(2-Methylpiperidin-1-yl)pyrazin-2-amine (CAS 1691092-15-5)
- 3-(3-Methylpiperidin-1-yl)pyrazin-2-amine (CAS 1691744-26-9)
- 3-(4-Methylpiperidin-1-yl)pyrazin-2-amine (CAS 1698522-47-2)
- 6-(4-Methylpiperidin-1-yl)pyridazin-3-amine (CAS 69184-67-4)
- 5-(2-Methylpiperidin-1-yl)furan-2-carbaldehyde (CAS 876710-46-2)
Recommended Standards
- 2-Methoxy-3-(1-methylpyrrolidin-2-yl)pyridine (CAS 1352512-48-1)
- 2-Methoxy-3-methyl-5-(pyrrolidin-2-yl)pyridine (CAS 1352518-50-3)
- 2,2'-Azobis(2-methylbutyronitrile) (CAS 13472-08-7)
- 1-(Cyclohexylmethyl)-1H-pyrazole-3-carbaldehyde (CAS 1352542-12-1)
- 2-Chloro-N-isopropylquinoline-6-carboxamide (CAS 921211-28-1)
- (2-Chloro-5-(difluoromethyl)-4-nitropyridin-3-yl)methanol (CAS 1806896-65-0)
- tert-Butyl 4-(2-((tert-butoxycarbonyl)amino)ethyl)piperidine-1-carboxylate (CAS 292135-37-6)
- [2-(3-methoxypropoxy)-4-methylphenyl]methanamine (CAS 1247807-01-7)
- 2-(Aminomethyl)-6-chloro-3-(difluoromethyl)pyridine (CAS 1805008-70-1)
- 2-Chloro-1-isopropyl-1h-imidazole (CAS 1053655-72-3)
- 6-(1H-Pyrazol-1-yl)-2,2'-bipyridine (CAS 135853-33-7)
- 1-(Pyridin-3-yl)-N-((tetrahydrofuran-2-yl)methyl)ethan-1-amine (CAS 1021069-91-9)
- N-(4-((Difluoromethyl)thio)phenyl)-4-phenylpiperazine-1-carbothioamide (CAS 454203-46-4)
- Semaglutide impurity 236 (CAS CATO-C4X-2226236)
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