Ethyl 4-bromo-7-chloro-1H-indole-2-carboxylate CAS 1352894-66-6
| CAS No. | 1352894-66-6 |
| Molecular Formula | C11H9BrClNO2 |
| Molecular Weight | 302.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 4-bromo-7-chloro-1H-indole-2-carboxylate.
Ethyl 4-bromo-7-chloro-1H-indole-2-carboxylate (CAS 1352894-66-6) is a high-purity analytical reference standard with the molecular formula C11H9BrClNO2 and a molecular weight of 302.55 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, Ethyl 4-bromo-7-chloro-1H-indole-2-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 302.55 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H9BrClNO2 |
| Molecular Weight | 302.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
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- Ethyl 7-bromo-4-chloro-1H-indole-2-carboxylate (CAS 1073494-43-5)
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- Ethyl 3-Bromo-4-chloroindole-1-carboxylate (CAS 1375064-58-6)
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Recommended Standards
- 6-Chloro-N-(3,4-dichlorophenyl)pyrazine-2-carboxamide (CAS 879131-40-5)
- 6-chloro-3-iodo-imidazo[1,2-b]pyridazin-2-amine (CAS 2097358-10-4)
- 6-chloro-3-iodo-1-methyl-pyrazolo[3,4-d]pyrimidine (CAS 2766312-12-1)
- 1-(3-Bromo-7-chloro-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)cyclopropan-1-ol (CAS 2387601-18-3)
- 4-(4-Acetyl-2-methoxy-5-nitrophenoxy)-butanoic Acid Ethyl Ester (CAS 1031702-80-3)
- 2-Bromo-3-chloro-5-fluoropyridine, 95% (CAS 1214326-94-9)
- 2-(2,4-Difluorophenyl)-2-oxoacetaldehyde (CAS 79784-36-4)
- 6-(4-Formylphenyl)nicotinaldehyde (CAS 885950-11-8)
- 6-(3-Methoxyphenyl)picolinimidamide hydrochloride (CAS 1179361-79-5)
- 2-Isopropyl-4,6-dimethyl-1,3,5-triazine (CAS 59101-59-6)
- 5-Fluoro-1-methylindolin-2-one (CAS 41192-31-8)
- 2-Hydrazinyl-7-(p-tolyl)thieno[3,2-d]pyrimidin-4(3H)-one (CAS 1779132-43-2)
- 6,7-Dimethoxy-3-phenyl-1,4-dihydroindeno[1,2-c]pyrazole (CAS 872872-09-8)
- Insulin Degludec Impurity 1 (CAS 843666-26-2)
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