3-Amino-1H-pyrazolo[4,3-b]pyridine-5-carboxylic acid methyl ester CAS 1352898-68-0
| CAS No. | 1352898-68-0 |
| Molecular Formula | C8H8N4O2 |
| Molecular Weight | 192.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Amino-1H-pyrazolo[4,3-b]pyridine-5-carboxylic acid methyl ester (CAS 1352898-68-0), molecular formula C8H8N4O2 and molecular weight 192.17 g/mol, is a CATO reference standard with documented purity and traceability.
3-Amino-1H-pyrazolo[4,3-b]pyridine-5-carboxylic acid methyl ester (C8H8N4O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 3-Amino-1H-pyrazolo[4,3-b]pyridine-5-carboxylic acid methyl ester under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8N4O2 |
| Molecular Weight | 192.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 4 |
Related Amino Standards
- 2-Amino-3-methyl-3H-imidazo[4,5-b]pyridine-6-carboxylic acid (CAS 1001754-93-3)
- Methyl 3-amino-5-cyano-2-hydroxybenzoate (CAS 1093397-34-2)
- Methyl 2-Amino-[1,2,4]triazolo[1,5-a]pyridine-6-carboxylate (CAS 1094107-41-1)
- 4-Amino-benzooxazole-2-carboxylic acid methyl ester (CAS 1187930-27-3)
- Methyl 3-amino-1H-pyrazolo[3,4-c]pyridine-5-carboxylate (CAS 1206973-28-5)
- 4-amino-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid (CAS 1332370-62-3)
- 4-Amino-6-methyl-6H-pyrrolo[3,4-d]pyrimidine-7-carboxylic acid (CAS 1368085-10-2)
- 4-(5-Amino-1H-1,2,4-triazol-3-yl)benzene-1,3-diol (CAS 1374408-48-6)
Recommended Standards
- 3,7-Dimethyl-6-oxo-6,7-dihydroisoxazolo[5,4-b]pyridine-5-carbaldehyde (CAS 1352534-45-2)
- 5-Nitro-3,4-dihydroisoquinolin-1(2H)-one (CAS 135329-21-4)
- 5-Methoxyimidazo[1,2-a]pyridine-2-carboxylic acid (CAS 1352398-56-1)
- 5-Methoxy-4-nitroindole (CAS 135531-92-9)
- N-((1-Ethyl-1H-pyrazol-5-yl)methyl)-1-propyl-1H-pyrazol-4-amine hydrochloride (CAS 1856039-69-4)
- 8-Methyl-8-azabicyclo[3.2.1]octan-2-one (CAS 78477-91-5)
- 2,6-Dimethyl-nicotinic acid hydrochloride (CAS 100960-91-6)
- Biotin-PEG4-OH (CAS 1217609-84-1)
- Perfluorophenyl 4-methyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-7-carboxylate (CAS 921938-83-2)
- 3-(2-Methylphenyl)benzaldehyde (CAS 371764-26-0)
- 4-Phenyltetrahydro-2H-pyran-4-ol (CAS 81462-07-9)
- N-Boc-DL-tyrosine (CAS 142847-18-5)
- N-((2,4-Dichloropyrimidin-5-yl)methyl)ethanamine (CAS 1289386-18-0)
- Prolactin-Releasing Peptide (12-31) (human) (CAS 235433-36-0)
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