1-(3-Fluoro-4-methylbenzyl)-6-(1-hydroxyethyl)-2,5-piperazinedione CAS 1353496-81-7
| CAS No. | 1353496-81-7 |
| Molecular Formula | C14H17FN2O3 |
| Molecular Weight | 280.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(3-Fluoro-4-methylbenzyl)-6-(1-hydroxyethyl)-2,5-piperazinedione (C14H17FN2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
1-(3-Fluoro-4-methylbenzyl)-6-(1-hydroxyethyl)-2,5-piperazinedione (CAS 1353496-81-7) is a high-purity analytical reference standard with the molecular formula C14H17FN2O3 and a molecular weight of 280.29 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(3-Fluoro-4-methylbenzyl)-6-(1-hydroxyethyl)-2,5-piperazinedione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H17FN2O3 |
| Molecular Weight | 280.29 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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- 7-Fluoro-5-oxo-2,3,4,5-tetrahydrobenzo[b]oxepin-8-yl pivalate (CAS 2226905-07-1)
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- 3-(3-Fluoro-4-methylphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde (CAS 956202-54-3)
- 2-(4-Fluoro-phenylamino)-N-(5-methyl-[1,3,4]thiadiazol-2-yl)-propionamide (CAS 1009155-54-7)
Recommended Standards
- Tert-butyl (3aR,6aR)-3a-(trifluoromethyl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate (CAS 1251004-14-4)
- 1-Benzyl-2-(4-(trifluoromethyl)benzyl)hydrazine (CAS 1392879-04-7)
- Tert-butyl (3aR,4S,6aR)-4-(trifluoromethyl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate (CAS 1251001-26-9)
- (S)-1-((R)-1-(2-fluorophenyl)-2-(methylamino)-2-oxoethyl)pyrrolidine-2-carboxylic acid (CAS 1421051-02-6)
- 2-(Bromomethyl)-5-(difluoromethoxy)pyridine (CAS 1375099-13-0)
- 2-(5-Chloro-2-fluorobenzenesulfonyl)-2-[(2E)-pyrrolidin-2-ylidene]acetonitrile (CAS 1454881-53-8)
- Potassiummu-oxobis[pentachlororuthenate(iv)] (CAS 16986-07-5)
- 2-Tetradecanol (CAS 4706-81-4)
- (+)-Epipinoresinol (CAS 24404-50-0)
- 5-(Ethanesulfonyl)-2-methyl-1,3-benzoxazole (CAS 847837-35-8)
- 1-Butyl-3-methylimidazolium Tribromide (CAS 820965-08-0)
- Benzyl 3-(2-aminoethoxy)pyrrolidine-1-carboxylate (CAS 1353962-15-8)
- Nicarbazine (CAS 330-95-0)
- Tirzepatide Impurity 17 (CAS CATO-C4X-324017)
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