3-Methyl-5-(trichloromethyl)-4,5-dihydroisoxazol-5-ol CAS 135351-22-3
| CAS No. | 135351-22-3 |
| Molecular Formula | C5H6Cl3NO2 |
| Molecular Weight | 218.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Methyl-5-(trichloromethyl)-4,5-dihydroisoxazol-5-ol (CAS 135351-22-3), molecular formula C5H6Cl3NO2 and molecular weight 218.47 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3-Methyl-5-(trichloromethyl)-4,5-dihydroisoxazol-5-ol (C5H6Cl3NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 218.47 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H6Cl3NO2 |
| Molecular Weight | 218.47 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 3-(Trichloromethyl)-1,2,4-thiadiazol-5(2h)-imine (CAS 7523-57-1)
- 2-(Trichloromethyl)benzonitrile (CAS 2635-68-9)
- 4-(trichloromethyl)benzonitrile (CAS 2179-45-5)
- 3-(Trichloromethyl)thiomorpholine (CAS 1452829-39-8)
- 3-ethyl-5-(trichloromethyl)-1,2,4-oxadiazole (CAS 1196-99-2)
- 2-(Trichloromethyl)pyrimidine-5-carbaldehyde (CAS 143034-45-1)
- 4-Methyl-4-(trichloromethyl)cyclohexa-2,5-dien-1-one (CAS 3274-12-2)
- 4-Methyl-6-(trichloromethyl)-1,3,5-triazin-2-amine (CAS 21227-47-4)
Recommended Standards
- Azetidin-3-yl 2,2,2-trichloroacetate (CAS 1219956-76-9)
- 1,1,3,3-Tetraethyl-1,3-dimethyldisiloxane (CAS 1000-00-6)
- 1-Chloro-4-iodobutane (CAS 10297-05-9)
- 3-Bromo-5-chloro-2-vinylpyridine (CAS 1256793-12-0)
- (2-Chloro-8-methoxyquinolin-3-yl)boronic acid (CAS 220506-64-9)
- (R)-5-(1-Methylpyrrolidin-2-yl)pyridin-2(1H)-one (CAS 22956-40-7)
- 2-((2,4-Dichlorobenzyl)amino)ethan-1-ol (CAS 6269-87-0)
- Tricyclo[2.1.0.02,5]pentan-3-one (CAS 31519-30-9)
- Tert-butyl 5'-chloro-1',4'-dihydro-2'h-spiro[piperidine-4,3'-quinoline]-1-carboxylate (CAS 2197055-63-1)
- Methyl 6-(tert-butylthio)-5-methylnicotinate (CAS 1355236-68-8)
- 6-Hydroxy-1,4-dimethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 27074-03-9)
- 5-Oxopyrrolidin-3-yl (3-fluorophenyl)carbamate (CAS 88036-84-4)
- (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propanoic acid (2S)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-phenylpropanoic acid 286460-71-7 A819517 (CAS 286460-71-7)
- (Des-Bromo)-Neuropeptide B (1-23) (human) (CAS 434897-64-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com