1-Bromo-4-(cyclopropylmethoxy)-2-fluorobenzene CAS 1353776-86-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1353776-86-9
Molecular FormulaC10H10BrFO
Molecular Weight245.09 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-Bromo-4-(cyclopropylmethoxy)-2-fluorobenzene CAS 1353776-86-9 chemical structure

Description

The occurrence of 1-Bromo-4-(cyclopropylmethoxy)-2-fluorobenzene is closely related to a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1-Bromo-4-(cyclopropylmethoxy)-2-fluorobenzene (CAS 1353776-86-9), molecular formula C10H10BrFO and molecular weight 245.09 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1-Bromo-4-(cyclopropylmethoxy)-2-fluorobenzene (C10H10BrFO) is characterized by a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H10BrFO
Molecular Weight245.09 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF/Br-containing

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