1-Bromo-2-cyclobutylbenzene CAS 1353854-80-4
| CAS No. | 1353854-80-4 |
| Molecular Formula | C10H11Br |
| Molecular Weight | 211.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 211.10 g/mol gives 1-Bromo-2-cyclobutylbenzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-Bromo-2-cyclobutylbenzene (CAS 1353854-80-4) is a high-purity analytical reference standard with the molecular formula C10H11Br and a molecular weight of 211.10 g/mol.
The molecular framework of 1-Bromo-2-cyclobutylbenzene (C10H11Br) is characterized by bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11Br |
| Molecular Weight | 211.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Br-containing |
Related Bromo Standards
- 1-Bromo-3-(1-methylcyclopropyl)benzene (CAS 1211592-89-0)
- 1-Bromo-2-(1-methylcyclopropyl)benzene (CAS 1211594-34-1)
- (3-Bromo-2-methylprop-1-en-1-yl)benzene (CAS 1282061-69-1)
- 1-Bromo-4-cyclopropyl-2-methylbenzene (CAS 1353854-72-4)
- 4-Bromo-1-(3-butenyl)benzene (CAS 15451-32-8)
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- 1-Bromo-4-(cyclopropylmethyl)benzene (CAS 179251-28-6)
Recommended Standards
- (trans-2-(bromomethyl)cyclopropyl)benzene (CAS 135911-95-4)
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- 1-(Bromomethyl)-3-cyclopropylbenzene (CAS 1260850-05-2)
- 1-(bromomethyl)-2-cyclopropylbenzene (CAS 1260801-90-8)
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