5-Chloro-3-hydroxy-2,3-dihydrobenzo[b]thiophene 1,1-dioxide CAS 1353878-07-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1353878-07-5
Molecular FormulaC8H7ClO3S
Molecular Weight218.66 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Chloro-3-hydroxy-2,3-dihydrobenzo[b]thiophene 1,1-dioxide CAS 1353878-07-5 chemical structure

Description

The occurrence of 5-Chloro-3-hydroxy-2,3-dihydrobenzo[b]thiophene 1,1-dioxide is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 5-Chloro-3-hydroxy-2,3-dihydrobenzo[b]thiophene 1,1-dioxide (CAS 1353878-07-5), a certified reference material (molecular formula C8H7ClO3S, MW 218.66 g/mol) for analytical method development and quality control.

The molecular framework of 5-Chloro-3-hydroxy-2,3-dihydrobenzo[b]thiophene 1,1-dioxide (C8H7ClO3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Chloro-3-hydroxy-2,3-dihydrobenzo[b]thiophene 1,1-dioxide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H7ClO3S
Molecular Weight218.66 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentCl-containing
Sulfur Atoms1

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