2-Chloro-N-(pyrrolidin-2-ylmethyl)nicotinamide hydrochloride CAS 1353956-66-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1353956-66-7
Molecular FormulaC11H14ClN3O
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Chloro-N-(pyrrolidin-2-ylmethyl)nicotinamide hydrochloride CAS 1353956-66-7 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-N-(pyrrolidin-2-ylmethyl)nicotinamide hydrochloride.

2-Chloro-N-(pyrrolidin-2-ylmethyl)nicotinamide hydrochloride (CAS 1353956-66-7), molecular formula C11H14ClN3OHCl and molecular weight 276.16 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 2-Chloro-N-(pyrrolidin-2-ylmethyl)nicotinamide hydrochloride (C11H14ClN3OHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 276.16 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Chloro-N-(pyrrolidin-2-ylmethyl)nicotinamide hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H14ClN3O HCl
Molecular Weight276.16 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentCl-containing
Nitrogen Atoms3

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