tert-Butyl 2-((2-chloronicotinamido)methyl)pyrrolidine-1-carboxylate CAS 1353974-16-9
| CAS No. | 1353974-16-9 |
| Molecular Formula | C16H22ClN3O3 |
| Molecular Weight | 339.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 339.82 g/mol gives tert-Butyl 2-((2-chloronicotinamido)methyl)pyrrolidine-1-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
tert-Butyl 2-((2-chloronicotinamido)methyl)pyrrolidine-1-carboxylate (CAS 1353974-16-9) is a high-purity analytical reference standard with the molecular formula C16H22ClN3O3 and a molecular weight of 339.82 g/mol.
tert-Butyl 2-((2-chloronicotinamido)methyl)pyrrolidine-1-carboxylate (C16H22ClN3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H22ClN3O3 |
| Molecular Weight | 339.82 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
- tert-Butyl 4-(2-chloronicotinamido)piperidine-1-carboxylate (CAS 1353973-88-2)
- tert-Butyl 4-(2-chloronicotinoyl)-2-methylpiperazine-1-carboxylate (CAS 1353978-39-8)
- Tert-butyl 3-(2-chloronicotinamido)piperidine-1-carboxylate (CAS 1353964-95-0)
- tert-Butyl (1-(2-chloronicotinoyl)piperidin-3-yl)carbamate (CAS 1353979-97-1)
- 1-(propan-2-yl)azetidin-3-ol hydrochloride (CAS 54431-32-2)
- 1-(2-Bromo-5-chlorobenzyl)-1H-pyrazol-4-ol (CAS 1880489-47-3)
- Methyl 3-amino-5-nitrobenzofuran-2-carboxylate (CAS 1779830-96-4)
- Methyl 4-((3-cyano-6-methyl-4-(thiophen-2-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)thio)-3-oxobutanoate (CAS 354554-86-2)
- JNJ 28871063 hydrochloride (CAS 944342-90-9)
- 2-(1-Aminocyclohexyl)pyrimidin-4(3H)-one (CAS 1342667-32-6)
- n-(Propan-2-yl)pyridin-3-amine (CAS 32405-76-8)
- H-γ-Glu-γ-Glu-Lys-OH (CAS 100922-54-1)
- PIK-90 (CAS 677338-12-4)
- D-Pro37-Tirzepatide (CAS CATO-CPTD788902)
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