N-((1-(2-Chloroacetyl)piperidin-3-yl)methyl)-N-isopropylacetamide CAS 1353976-74-5
| CAS No. | 1353976-74-5 |
| Molecular Formula | C13H23ClN2O2 |
| Molecular Weight | 274.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-((1-(2-Chloroacetyl)piperidin-3-yl)methyl)-N-isopropylacetamide (CAS 1353976-74-5), molecular formula C13H23ClN2O2 and molecular weight 274.79 g/mol, is a CATO reference standard with documented purity and traceability.
N-((1-(2-Chloroacetyl)piperidin-3-yl)methyl)-N-isopropylacetamide (C13H23ClN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-((1-(2-Chloroacetyl)piperidin-3-yl)methyl)-N-isopropylacetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H23ClN2O2 |
| Molecular Weight | 274.79 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- 1-(2-chloroacetyl)-N-(3-methylbutyl)piperidine-4-carboxamide (CAS 1308650-28-3)
- N-((1-(2-Chloroacetyl)piperidin-4-yl)methyl)-N-isopropylacetamide (CAS 1353965-66-8)
- N-((1-(2-Chloroacetyl)piperidin-2-yl)methyl)-N-isopropylacetamide (CAS 1353968-86-1)
- 3-[1-(chloroacetyl)-1,2,3,6-tetrahydropyridin-4-yl]-1H-indole (CAS 1087792-03-7)
- 1-(chloroacetyl)indoline-5-sulfonamide (CAS 929973-97-7)
- 10-(Chloroacetyl)-10H-phenothiazine (CAS 786-50-5)
- n-[4-(2-chloroacetyl)phenyl]-n-ethylmethanesulfonamide (CAS 851814-23-8)
- n-{2-[4-(2-chloroacetyl)phenyl]ethyl}methanesulfonamide (CAS 875159-59-4)
Recommended Standards
- 2,5,7-Trimethylbenzo[b]thiophene-3-sulfonyl chloride (CAS 1384429-25-7)
- 2,4,7-Trimethylbenzo[b]thiophene-3-sulfonyl chloride (CAS 1384430-95-8)
- 2-Chloro-N-(4-(N-isopropylacetamido)cyclohexyl)acetamide (CAS 1353952-36-9)
- 5-chloro-1-(3-ethoxypropyl)-1H-1,3-benzodiazole-2-carbaldehyde (CAS 1437435-52-3)
- 3-(Benzenesulfonyl)-4-methyl-6-phenyl-1-{[3-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridin-2-one (CAS 321431-33-8)
- (4Z)-4-(2-Amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-2-bromo-4,5,6,7-tetrahydro-pyrrolo[2,3-c]azepin-8(1H)-one Methanoate (Z)-Hymenialdisine Methanoate 84094-94-0 Hymenialdisine Methanoate (CAS 84094-94-0)
- KPT-276 (CAS 1421919-75-6)
- 7,8-Dimethoxy-3,4-dihydroisoquinoline Hydrochloride (CAS 29983-75-3)
- Methyl 6-methyl-1-oxaspiro[2.6]nonane-2-carboxylate (CAS 1560733-10-9)
- 1-(3-Fluoro-5-methylphenyl)cyclopropanamine (CAS 1266144-29-9)
- 3-(2-Bromo-5-methoxybenzyl)oxetane (CAS 1823348-98-6)
- Ethyl 6-chloro-4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate (CAS 958332-77-9)
- 1-[4-(1-Methyl-1H-imidazol-5-yl)phenyl]ethan-1-one (CAS 1333127-93-7)
- Neuropeptide FF (5-8) (CAS 152050-35-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com