(S)-tert-Butyl (1-(2-chloroacetyl)pyrrolidin-3-yl)(isopropyl)carbamate CAS 1354003-02-3
| CAS No. | 1354003-02-3 |
| Molecular Formula | C14H25ClN2O3 |
| Molecular Weight | 304.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
(S)-tert-Butyl (1-(2-chloroacetyl)pyrrolidin-3-yl)(isopropyl)carbamate (CAS 1354003-02-3) is a high-purity analytical reference standard with the molecular formula C14H25ClN2O3 and a molecular weight of 304.81 g/mol.
The molecular framework of (S)-tert-Butyl (1-(2-chloroacetyl)pyrrolidin-3-yl)(isopropyl)carbamate (C14H25ClN2O3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H25ClN2O3 |
| Molecular Weight | 304.81 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- [1-(2-Chloro-acetyl)-piperidin-3-yl]-methyl-carbamic acid tert-butyl ester (CAS 1354002-78-0)
- (S)-tert-Butyl ((1-(2-chloroacetyl)pyrrolidin-2-yl)methyl)(ethyl)carbamate (CAS 1354003-24-9)
- (S)-tert-Butyl 3-(2-chloro-N-isopropylacetamido)pyrrolidine-1-carboxylate (CAS 1353998-23-8)
- (R)-tert-Butyl (1-(2-chloroacetyl)pyrrolidin-3-yl)(isopropyl)carbamate (CAS 1354019-44-5)
- tert-Butyl (2-(2-acetylhydrazinyl)-2-oxoethyl)carbamate (CAS 388630-68-0)
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