5-Chloro-2-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)aniline CAS 135436-95-2
| CAS No. | 135436-95-2 |
| Molecular Formula | C11H10ClN3O |
| Molecular Weight | 235.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Chloro-2-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)aniline (CAS 135436-95-2), molecular formula C11H10ClN3O and molecular weight 235.67 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Chloro-2-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)aniline (C11H10ClN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Chloro-2-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)aniline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H10ClN3O |
| Molecular Weight | 235.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- 2-(tert-Butyl)-4-chlorooxazolo[4,5-c]pyridine-7-carbonitrile (CAS 1346447-42-4)
- 6-Chloro-9-(3-methylenecyclobutyl)-9H-purin-2-amine (CAS 136137-59-2)
- 4-(Benzyloxy)-6-chloropyrimidin-5-amine (CAS 1344227-47-9)
- 2-(2-Chlorophenyl)-4-methyl-1H-pyrrole-3-carboxylic acid (CAS 1364523-61-4)
- 2-Isopropylpyrazolo[1,5-a]pyrimidin-6-amine hydrochloride (CAS 1707358-53-9)
- 3-(bromomethyl)benzofuran (CAS 38281-49-1)
- (2-Methoxyphenyl)(6-methylpyridin-3-yl)methanone (CAS 1187163-95-6)
- 6-(2,2,2-Trifluoroethoxy)picolinic acid (CAS 1247503-48-5)
- 2,2',2''-(1H-Imidazole-2,4,5-triyl)tripyridine (CAS 23974-92-7)
- 4-Bromo-6-chloro-2-(methylthio)pyrimidine (CAS 1563530-34-6)
- 1-(2-Bromopyridin-3-yl)propan-1-one (CAS 123534-58-7)
- Amlodipine Impurity N21 (CAS 2170111-18-7)
- tert-Butyl 5-(2-(2-cyanopropan-2-yl)pyridin-4-yl)-4-methylthiazol-2-ylcarbamate (CAS 1217486-72-0)
- Insulin Degludec Impurity 15 (CAS CATO-C4X-215715)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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