Methyl (3R,4R)-4-hydroxypyrrolidine-3-carboxylate hydrochloride CAS 1354423-46-3
| CAS No. | 1354423-46-3 |
| Molecular Formula | C6H11NO3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl (3R,4R)-4-hydroxypyrrolidine-3-carboxylate hydrochloride.
Methyl (3R,4R)-4-hydroxypyrrolidine-3-carboxylate hydrochloride (CAS 1354423-46-3) is a high-purity analytical reference standard with the molecular formula C6H11NO3HCl and a molecular weight of 181.62 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Methyl (3R,4R)-4-hydroxypyrrolidine-3-carboxylate hydrochloride is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 181.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H11NO3 HCl |
| Molecular Weight | 181.62 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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