(2S,4S)-1-(tert-butoxycarbonyl)-4-(2,4-dimethylphenoxy)pyrrolidine-2-carboxylic acid CAS 1354485-91-8
| CAS No. | 1354485-91-8 |
| Molecular Formula | C18H25NO5 |
| Molecular Weight | 335.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(2S,4S)-1-(tert-butoxycarbonyl)-4-(2,4-dimethylphenoxy)pyrrolidine-2-carboxylic acid (CAS 1354485-91-8), molecular formula C18H25NO5 and molecular weight 335.39 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, (2S,4S)-1-(tert-butoxycarbonyl)-4-(2,4-dimethylphenoxy)pyrrolidine-2-carboxylic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 335.39 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H25NO5 |
| Molecular Weight | 335.39 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
Recommended Standards
- (2S,4S)-1-(tert-butoxycarbonyl)-4-(3-ethylphenoxy)pyrrolidine-2-carboxylic acid (CAS 1354485-37-2)
- (2S,4S)-1-(tert-butoxycarbonyl)-4-(3,4-dimethylphenoxy)pyrrolidine-2-carboxylic acid (CAS 1354486-23-9)
- (2S,4S)-1-(tert-Butoxycarbonyl)-4-(2,3-dimethyl-phenoxy)-2-pyrrolidinecarboxylic acid (CAS 1354484-54-0)
- (2S,4S)-1-(tert-Butoxycarbonyl)-4-(4-ethyl-phenoxy)-2-pyrrolidinecarboxylic acid (CAS 1354487-05-0)
- Hexakis[μ-(acetato-O:O')]-triaqua-μ3-oxotriruthenium(III) (CAS 38998-79-7)
- (1S)-1-(1,3-thiazol-5-yl)ethan-1-amine dihydrochloride (CAS 1807938-52-8)
- 2-(1,1-Dimethylethyl) 1-(phenylmethyl) (2S)-4-oxo-1,2-pyrrolidinedicarboxylate (CAS 898391-86-1)
- Benzyl (1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-3-yl)carbamate (CAS 1354029-55-2)
- 3-(p-Tolyl)-1H-1,2,4-triazole (CAS 23195-60-0)
- 2-Bromo-3’-(trifluoromethyl)acetophenone (CAS 2003-10-3)
- 7-Hydroxy-6-propyl-2,3-dihydro-1H,5H-pyrido[3,2,1-ij]quinolin-5-one (CAS 57625-51-1)
- (S)-3-(2-Bromo-5-fluorophenoxy)pyrrolidine hydrochloride (CAS 960491-90-1)
- n-Amino-4-chloropyridine-2-carboximidamide (CAS 1192456-28-2)
- Peptide YY (13-36) (canine, mouse, porcine, rat) (CAS 86895-09-2)
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