4-(Pent-4-yn-1-yl)cyclohexane-1,3-dione CAS 1354630-46-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1354630-46-8
Molecular FormulaC11H14O2
Molecular Weight178.23 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(Pent-4-yn-1-yl)cyclohexane-1,3-dione CAS 1354630-46-8 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(Pent-4-yn-1-yl)cyclohexane-1,3-dione.

4-(Pent-4-yn-1-yl)cyclohexane-1,3-dione (CAS 1354630-46-8) is a high-purity analytical reference standard with the molecular formula C11H14O2 and a molecular weight of 178.23 g/mol.

The molecular framework of 4-(Pent-4-yn-1-yl)cyclohexane-1,3-dione (C11H14O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H14O2
Molecular Weight178.23 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991

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