Leniolisib CAS 1354690-24-6
| CAS No. | 1354690-24-6 |
| Molecular Formula | C21H25F3N6O2 |
| Molecular Weight | 450.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Leniolisib (CAS 1354690-24-6), a certified reference material (molecular formula C21H25F3N6O2, MW 450.46 g/mol) for analytical method development and quality control.
Leniolisib (C21H25F3N6O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Leniolisib meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H25F3N6O2 |
| Molecular Weight | 450.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Recommended Standards
- Epristeride Impurity 5 (CAS CATO-C4X-30085)
- (S)-ethyl 2-(2-benzyl-3-(4-nitrophenylsulfonyloxy)propanamido)acetate (CAS 1404514-08-4)
- Epristeride Impurity 1 (CAS 163889-78-9)
- Ethyl 2-(2-benzyl-3-(((4-nitrophenyl)sulfonyl)oxy)propanamido)acetate (CAS 1431697-91-4)
- 2-Bromo-4-isopropylbenzenesulfonyl chloride (CAS 1027513-69-4)
- 2-hydroxy-3-methylbut-3-enenitrile (CAS 22410-56-6)
- N-(2,3-Dimethylphenyl)-3-nitrobenzenesulfonamide (CAS 250697-59-7)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(2-(tert-butoxy)-2-oxoethyl)phenyl)propanoic acid (CAS 222842-99-1)
- N-1-Benzyl-N-1-methyl-2-(trifluoromethyl)-1,4-benzenediamine (CAS 1179928-61-0)
- 4-Hydroxylamino-2,6-dinitrotoluene (CAS 59283-75-9)
- N-(2-((3-(3-cyanophenoxy)-2-hydroxypropyl)amino)ethyl)morpholine-4-carboxamide (CAS 1638768-72-5)
- N-(3,5-dimethylphenyl)-2-morpholinoacetamide (CAS 329079-41-6)
- Methyl 4-Amino-6-indolecarboxylate Hydrochloride (CAS 1235138-34-7)
- Heptapeptide-6 (CAS CATO-CPTD788823)
Why CATO?
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