3-Bromo-5-methyl-1-(2,2,2-trifluoroethyl)-1H-pyrazole CAS 1354704-62-3
| CAS No. | 1354704-62-3 |
| Molecular Formula | C6H6BrF3N2 |
| Molecular Weight | 243.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Bromo-5-methyl-1-(2,2,2-trifluoroethyl)-1H-pyrazole (CAS 1354704-62-3), molecular formula C6H6BrF3N2 and molecular weight 243.02 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Bromo-5-methyl-1-(2,2,2-trifluoroethyl)-1H-pyrazole (C6H6BrF3N2) is characterized by a nitrile group, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Bromo-5-methyl-1-(2,2,2-trifluoroethyl)-1H-pyrazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6BrF3N2 |
| Molecular Weight | 243.02 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 7-Bromo-4-nitro-1H-benzo[d][1,2,3]triazole (CAS 1228575-46-9)
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Recommended Standards
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- 2-Propenoic acid, 2-methyl-, polymer with ethyl 2-propenoate and 6-(4-penten-1-yl)-1,3,5-triazine-2,4-diamine (CAS 65859-25-8)
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