1-(Difluoromethyl)-4-iodo-5-methyl-1H-pyrazole CAS 1354705-44-4
| CAS No. | 1354705-44-4 |
| Molecular Formula | C5H5F2IN2 |
| Molecular Weight | 258.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 1-(Difluoromethyl)-4-iodo-5-methyl-1H-pyrazole (CAS 1354705-44-4), a certified reference material (molecular formula C5H5F2IN2, MW 258.01 g/mol) for analytical method development and quality control.
1-(Difluoromethyl)-4-iodo-5-methyl-1H-pyrazole (C5H5F2IN2) contains a nitrile group, fluorine/iodine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C5H5F2IN2 |
| Molecular Weight | 258.01 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 2 |
Related Difluoromethyl Standards
- 1-(Difluoromethyl)-4-iodo-3-methyl-1h-pyrazole (CAS 1217862-89-9)
- 3-(Difluoromethyl)-4-iodo-1-methyl-1H-pyrazole (CAS 1856047-69-2)
- 5-(Difluoromethyl)-4-iodo-1-methyl-1H-pyrazole (CAS 1856051-59-6)
- 1-(Difluoromethyl)-4-iodo-2-methyl-1H-imidazole (CAS 2755894-00-7)
- 4-(Difluoromethyl)-3-iodo-1-methyl-1H-pyrazole (CAS 2137519-48-1)
- 1-(Difluoromethyl)-3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 2675491-23-1)
- 1-(Difluoromethyl)-5-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 2732864-03-6)
- 3-(Difluoromethyl)-1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 2197909-48-9)
Recommended Standards
- 1-(2,2-Difluoroethyl)-4-iodo-1H-pyrazole (CAS 1344078-17-6)
- 2-Chloro-1-[chloro(difluoro)-methoxy]-3-nitro-benzene (CAS 1417566-50-7)
- 3-Bromo-2-fluoro-5-(trifluoromethyl)aniline (CAS 1262198-06-0)
- 4-Chloro-2-[chloro(difluoro)-methoxy]-1-nitro-benzene (CAS 1417566-69-8)
- n-((5-Bromothiophen-2-yl)methyl)-2-hydroxy-4-methylbenzamide (CAS 1100130-19-5)
- 1-(bromomethyl)-3,5-difluoro-2-methoxybenzene (CAS 886500-63-6)
- [1-(Tetrahydrofuran-3-yl)cyclopropyl]-amine hydrochloride (CAS 1417568-93-4)
- (3S,4R)-4-butylpyrrolidin-3-ol (CAS 1242166-62-6)
- (6-(Ethylcarbamoyl)pyridin-3-yl)boronic acid (CAS 944794-82-5)
- Isochroman-4-ol (CAS 20924-57-6)
- 1024375-31-2 3-(3,4-Dichlorophenyl)-1-(4-((6,7-dimethoxy(3,4-dihydroisoquinolyl))methyl)phenyl)urea MFCD03839406 (CAS 1024375-31-2)
- Methyl 3-Cyanophenylacetate (CAS 52798-00-2)
- 2-(4-(Difluoromethyl)-5-nitropyridin-2-yl)acetic acid (CAS 1805326-90-2)
- Crustacean Cardioactive Peptide (CCAP) (CAS 309247-84-5)
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