3-Amino-1-ethyl-4-iodo-1H-pyrazole-5-carboxylic acid CAS 1354705-84-2
| CAS No. | 1354705-84-2 |
| Molecular Formula | C6H8IN3O2 |
| Molecular Weight | 281.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 281.05 g/mol gives 3-Amino-1-ethyl-4-iodo-1H-pyrazole-5-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-Amino-1-ethyl-4-iodo-1H-pyrazole-5-carboxylic acid (CAS 1354705-84-2), a certified reference material (molecular formula C6H8IN3O2, MW 281.05 g/mol) for analytical method development and quality control.
The molecular framework of 3-Amino-1-ethyl-4-iodo-1H-pyrazole-5-carboxylic acid (C6H8IN3O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H8IN3O2 |
| Molecular Weight | 281.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- Methyl 3-amino-4-iodo-1-methyl-1H-pyrazole-5-carboxylate (CAS 1354704-00-9)
- 6-Amino-1-ethyl-5-iodopyrimidine-2,4(1H,3H)-dione (CAS 1549752-63-7)
- 2-(4-Amino-3-bromo-5-(difluoromethyl)pyridin-2-yl)acetic acid (CAS 1804721-38-7)
- 2-Amino-5-(bromomethyl)-6-(difluoromethyl)nicotinic acid (CAS 1804725-35-6)
- 2-(6-Amino-5-bromo-4-(difluoromethyl)pyridin-2-yl)acetic acid (CAS 1805054-97-0)
- 2-(6-Amino-5-bromo-4-(difluoromethyl)pyridin-3-yl)acetic acid (CAS 1805092-32-3)
- 2-(2-Amino-5-bromo-3-(difluoromethyl)pyridin-4-yl)acetic acid (CAS 1805092-65-2)
- 2-(4-Amino-5-bromo-3-(difluoromethyl)pyridin-2-yl)acetic acid (CAS 1805093-07-5)
Recommended Standards
- 1-Ethyl-4-iodo-5-methyl-3-nitro-1H-pyrazole (CAS 1354705-45-5)
- Ethyl 4-iodo-5-methylisoxazole-3-carboxylate (CAS 1356600-24-2)
- 4-Iodo-3-nitro-1-propyl-1H-pyrazole (CAS 1354704-96-3)
- (4-Iodo-3-methylisoxazol-5-yl)acetic acid methyl ester (CAS 1356600-44-6)
- 1-[2-(trifluoromethyl)phenyl]imidazolidin-2-one (CAS 1550068-19-3)
- 3-Bromo-2-fluoro-5-(trifluoromethyl)benzyl alcohol (CAS 2092564-68-4)
- 2-Amino-4-(3,4-dimethoxyphenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 170940-62-2)
- (4-(3-Methyl-1H-pyrazol-1-yl)-2-(trifluoromethyl)phenyl)boronic acid (CAS 2225178-52-7)
- 1-(3-(2,2,2-Trifluoroethoxy)pyridin-4-yl)ethanone (CAS 1427522-50-6)
- N-(2-Hydroxyethyl)-4-propoxynaphthalene-1-sulfonamide (CAS 1206105-01-2)
- 4-(4-Fluorobenzoyl)-1-methyl-1H-pyrrole-2-carbaldehyde (CAS 128843-61-8)
- 1-(3-Bromopyridin-4-yl)cyclopropan-1-amine hydrochloride (CAS 2149602-41-3)
- 1313825-26-1 2-(3-phenylpyrrolidin-1-yl)acetohydrazide (CAS 1313825-26-1)
- Semaglutide impurity 251 (CAS CATO-C4X-2226251)
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