(S)-Fmoc-2-amino-6-tert-butoxy-hexanoic acid CAS 1354752-71-8
| CAS No. | 1354752-71-8 |
| Molecular Formula | C25H31NO5 |
| Molecular Weight | 425.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(S)-Fmoc-2-amino-6-tert-butoxy-hexanoic acid (CAS 1354752-71-8) is a high-purity analytical reference standard with the molecular formula C25H31NO5 and a molecular weight of 425.52 g/mol.
The molecular framework of (S)-Fmoc-2-amino-6-tert-butoxy-hexanoic acid (C25H31NO5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), (S)-Fmoc-2-amino-6-tert-butoxy-hexanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H31NO5 |
| Molecular Weight | 425.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
Related S Standards
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- Fmoc-D-β-HoAsp(OtBu)-OH (CAS 1246651-90-0)
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Recommended Standards
- (2S,4S)-1-(tert-butoxycarbonyl)-4-(4-(2-phenylpropan-2-yl)phenoxy)pyrrolidine-2-carboxylic acid (CAS 1354485-42-9)
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- 4-(Difluoromethyl)-2-(trifluoromethoxy)-5-(trifluoromethyl)pyridin-3-ol (CAS 1804776-18-8)
- 3-(Aminomethyl)-6-(difluoromethyl)-5-iodopyridin-2-amine (CAS 1803670-98-5)
- 3-Hydroxy-1lambda6-thiane-1,1-dione (CAS 94158-05-1)
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