2-Chloro-4-(6-chlorooxazolo[5,4-b]pyridin-2-yl)aniline CAS 1354757-74-6
| CAS No. | 1354757-74-6 |
| Molecular Formula | C12H7Cl2N3O |
| Molecular Weight | 280.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-4-(6-chlorooxazolo[5,4-b]pyridin-2-yl)aniline.
CATO supplies 2-Chloro-4-(6-chlorooxazolo[5,4-b]pyridin-2-yl)aniline (CAS 1354757-74-6), a certified reference material (molecular formula C12H7Cl2N3O, MW 280.11 g/mol) for analytical method development and quality control.
2-Chloro-4-(6-chlorooxazolo[5,4-b]pyridin-2-yl)aniline (C12H7Cl2N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H7Cl2N3O |
| Molecular Weight | 280.11 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 3-Chloro-4-(6-chlorooxazolo[5,4-b]pyridin-2-yl)aniline (CAS 1354750-96-1)
- 4-Chloro-2-(6-chlorooxazolo[5,4-b]pyridin-2-yl)aniline (CAS 1354760-74-9)
- 2-Chloro-5-(6-chlorooxazolo[5,4-b]pyridin-2-yl)aniline (CAS 1354778-26-9)
- 2-Chloro-N-(3-chlorophenyl)-9H-purin-6-amine (CAS 190654-76-3)
- 3-Chloro-5-(2-chloro-5-hydroxyphenoxy)benzonitrile (CAS 920036-12-0)
- 3-Chloro-5-(5-chloro-2-hydroxyphenoxy)benzonitrile (CAS 895572-24-4)
- 4-Chloro-N-(4-chlorophenyl)furo[2,3-d]pyridazin-7-amine (CAS 332013-41-9)
- 7-Chloro-3-(2-chlorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine (CAS 201541-70-0)
Recommended Standards
- 2-(2,6-Dichlorophenyl)-1H-imidazo[4,5-c]pyridin-4-ol (CAS 1334411-80-1)
- 2-(2,6-Dichlorophenyl)-1,2-dihydro-3H-pyrazolo[3,4-c]pyridin-3-one (CAS 1313738-66-7)
- Dimethyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)phosphine oxide (CAS 1394346-20-3)
- 2-(2,6-DIchloro-phenyl)-1,2-dihydropyrazolo[3,4-c]pyridin-3-one (CAS 131373-86-9)
- 3-Bromo-2-methylpyrazolo[1,5-d][1,2,4]triazin-4(5H)-one (CAS 1225193-83-8)
- 2,2-Difluorocyclopropane-1-carboximidamide (CAS 1393570-10-9)
- (R)-2-amino-2-(2-fluorophenyl)propan-1-ol (CAS 1213310-23-6)
- tert-Butyl (S)-2-(5-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)thiazol-2-yl)pyrrolidine-1-carboxylate (CAS 1256384-74-3)
- 2,2'-((3-(Trifluoromethyl)phenyl)azanediyl)diethanol (CAS 323-79-5)
- 4,7-Dichloro-8-methylquinoline 643039-79-6 C10H7Cl2N V7088 (CAS 643039-79-6)
- N-(4,5,6,7-Tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)thiophene-3-carboxamide hydrochloride (CAS 1421457-85-3)
- 2-(5-Bromo-2-methylbenzo[d]oxazol-7-yl)acetonitrile (CAS 1708168-02-8)
- 1-(2-Piperidinylmethyl)-4-piperidinoldihydrochloride (CAS 1219964-35-8)
- Semaglutide Impurity 128 (CAS 2490269-78-6)
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