Tert-butyl 4-(4-fluoro-3-(trifluoromethyl)phenyl)-3-oxopiperidine-1-carboxylate CAS 1354953-08-4
| CAS No. | 1354953-08-4 |
| Molecular Formula | C17H19F4NO3 |
| Molecular Weight | 361.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Tert-butyl 4-(4-fluoro-3-(trifluoromethyl)phenyl)-3-oxopiperidine-1-carboxylate (C17H19F4NO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 361.33 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Tert-butyl 4-(4-fluoro-3-(trifluoromethyl)phenyl)-3-oxopiperidine-1-carboxylate (CAS 1354953-08-4) is a high-purity analytical reference standard with the molecular formula C17H19F4NO3 and a molecular weight of 361.33 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Tert-butyl 4-(4-fluoro-3-(trifluoromethyl)phenyl)-3-oxopiperidine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H19F4NO3 |
| Molecular Weight | 361.33 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- N,N-dimethyl-4-oxo-3-(3-(trifluoromethyl)phenyl)-3,4-dihydrophthalazine-1-carboxamide (CAS 338975-89-6)
- (2R,3R,4S,5R)-2-(6-((3-Fluorophenyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 29204-64-6)
- N-(4-methoxyphenyl)-1-phenyl-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 956742-03-3)
- (2R,3R,4S,5R)-2-(6-Amino-8-(4-fluorophenyl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 73340-79-1)
- 6,7-Dimethoxy-3,4-dihydroisoquinoline-2(1H)-carboximidamide hydroiodide (CAS 849776-51-8)
- 1,3-Bis(prop-2-yl)-1H-imidazol-3-ium tetrafluoroborate 1,3-diisopropylimidazol-1-ium tetrafluoroborate 286014-34-4 (CAS 286014-34-4)
- Rac-(3ar,6ar)-5-(4-fluorobenzoyl)-octahydropyrrolo[3,4-b]pyrrole, cis (CAS 1218478-47-7)
- Cis-3-ethoxy-1,1,5-trimethylcyclohexane (CAS 24691-15-4)
- 2-Ethyl-4-methyl-6-oxo-1,6-dihydropyrimidine-5-carbonitrile (CAS 950032-36-7)
- 5-(4-Cyclohexylphenyl)-1H-pyrazole-3-carboxylic acid (CAS 1039041-18-3)
- 3-Morpholin-4-yl-propionic acid hydrochloride (CAS 6319-95-5)
- 2-((2-Cyano-3-methylbutan-2-yl)amino)-2-oxoethyl (2-phenylacetyl)valinate (CAS 1008409-98-0)
- 2-O-(α-D-Mannopyranosyl)-D-mannopyranose (CAS 15548-39-7)
- Boc-Cholecystokinin Octapeptide (desulfated) (A-1295.0001) (CAS 25687-34-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com