Tert-butyl 4-(3,5-difluorophenyl)-3-oxopiperidine-1-carboxylate CAS 1354959-49-1
| CAS No. | 1354959-49-1 |
| Molecular Formula | C16H19F2NO3 |
| Molecular Weight | 311.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 311.32 g/mol gives Tert-butyl 4-(3,5-difluorophenyl)-3-oxopiperidine-1-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Tert-butyl 4-(3,5-difluorophenyl)-3-oxopiperidine-1-carboxylate (CAS 1354959-49-1) is a high-purity analytical reference standard with the molecular formula C16H19F2NO3 and a molecular weight of 311.32 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Tert-butyl 4-(3,5-difluorophenyl)-3-oxopiperidine-1-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 311.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Tert-butyl 4-(3,5-difluorophenyl)-3-oxopiperidine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H19F2NO3 |
| Molecular Weight | 311.32 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 3-[4-(trifluoromethyl)benzoyl]-4H,5H,6H-cyclopenta[b]thiophen-2-amine (CAS 1256257-04-1)
- Tert-butyl ((1S,2S)-1-(2,5-difluorophenyl)-1-hydroxypent-4-yn-2-yl)carbamate (CAS 1417402-42-6)
- Olaparib impurity 143 (CAS CATO-C4X-1135143)
- 3-(1-(Thiazol-2-yl)-1H-imidazol-4-yl)imidazo[1,5-a]pyridine-1-carboxylic acid (CAS 1422068-91-4)
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- 2-BROMO-3-CHLOROPHENYLACETIC ACID (CAS 1261775-55-6)
- 1-(4-Chlorophenyl)-2,5-dimethyl-1h-pyrrole-3-carbaldehyde (CAS 20461-26-1)
- (2S,4R)-4-Acetoxypyrrolidine-2-carboxylic acid (CAS 46122-47-8)
- 1,2-Ethanediylbis(imino-2,1-ethanediyl) (9Z)-octadecenate dihydrochloride (CAS 167951-94-2)
- 1-(4-Methyl-6-phenoxypyridin-3-yl)ethan-1-ol (CAS 1355192-21-0)
- Semaglutide Impurity 147 (CAS CATO-C4X-2226147)
Why CATO?
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