3-(piperidin-1-ylmethyl)pyridine-2-carbonitrile hydrochloride CAS 1354963-46-4
| CAS No. | 1354963-46-4 |
| Molecular Formula | C12H15N3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(piperidin-1-ylmethyl)pyridine-2-carbonitrile hydrochloride.
3-(piperidin-1-ylmethyl)pyridine-2-carbonitrile hydrochloride (CAS 1354963-46-4) is a high-purity analytical reference standard with the molecular formula C12H15N3HCl and a molecular weight of 237.73 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 3-(piperidin-1-ylmethyl)pyridine-2-carbonitrile hydrochloride is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 237.73 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(piperidin-1-ylmethyl)pyridine-2-carbonitrile hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H15N3 HCl |
| Molecular Weight | 237.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related piperidin Standards
- 1000339-76-3 Ethyl 2-(Piperidin-1-yl)-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate ethyl 2-(piperidin-1-yl)-4-trifluoromethyl-1,3-thiazole-5-carboxylate ethyl 2-piperidin-1-yl-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate (CAS 1000339-76-3)
- 2-(Piperidin-1-yl)-4-(trifluoromethyl)thiazole-5-carboxylic acid (CAS 1000339-77-4)
- Benzyl 2-(piperidin-4-yl)acetate hydrochloride (CAS 1000872-47-8)
- n-(Piperidin-3-ylmethyl)morpholine-4-carboxamide (CAS 1000941-33-2)
- 1000958-55-3 4-Ethyl-1-[2-(piperidin-4-yl)ethyl]piperidine DTXSID60649257 (CAS 1000958-55-3)
- 5-(Piperidin-2-yl)pyridin-2-amine (CAS 100133-12-8)
- 5-(Piperidin-1-ylmethyl)pyrimidine-2,4(1H,3H)-dione (CAS 100133-53-7)
- 1-methyl-5-(piperidin-1-ylcarbonyl)-1H-pyrazol-4-amine (CAS 1001500-82-8)
Recommended Standards
- MXDA polyamide (CAS 128554-52-9)
- Metribuzin-desamino-desmethyl (CAS 66392-60-7)
- 2-(2-(Cyclopentylmethoxy)ethoxy)ethane-1-sulfonyl chloride (CAS 1515751-31-1)
- (S)-Benzyl 3-((S)-2-amino-3-methylbutanamido)pyrrolidine-1-carboxylate (CAS 1401665-33-5)
- 1-(Benzo[d][1,3]dioxol-5-yl)cyclopropane-1-carbaldehyde (CAS 33522-15-5)
- 3-(9-Fluoro-1,2,3,4-tetrahydro-[1,4]diazepino[6,7,1-hi]indol-7-yl)-4-(imidazo[1,2-a]pyridin-3-yl)-1H-pyrrole-2,5-dione dihydrochloride (CAS 1248570-14-0)
- (2R,3R,4R,5R)-4-(4-(1H-Imidazol-1-yl)butoxy)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol (CAS 165381-57-7)
- Cefprozil (E)-Isomer (CAS 92676-86-3)
- 1-(Furan-2-yl)propan-1-amine (CAS 59915-99-0)
- Semaglutide impurity 108 (CAS CATO-C4X-2226108)
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