3-Chloro-6-methoxy-1-methyl-1H-indole-2-carboxylic acid CAS 1355179-52-0
| CAS No. | 1355179-52-0 |
| Molecular Formula | C11H10ClNO3 |
| Molecular Weight | 239.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-Chloro-6-methoxy-1-methyl-1H-indole-2-carboxylic acid (CAS 1355179-52-0), molecular formula C11H10ClNO3 and molecular weight 239.66 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Chloro-6-methoxy-1-methyl-1H-indole-2-carboxylic acid (C11H10ClNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H10ClNO3 |
| Molecular Weight | 239.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- 3-[4-(2-chloroacetyl)phenyl]-1,3-oxazolidin-2-one (CAS 1354950-60-9)
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- 6-Chloro-1-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1354822-20-0)
- 6-Chloro-5-methoxy-3-methyl-1H-indole-2-carboxylic acid (CAS 1368490-62-3)
- 1-(2-Amino-6-methoxyphenyl)-2,2,2-trifluoroethan-1-one (CAS 1233967-21-9)
- 2-Oxo-5-(trifluoromethyl)-1,2-dihydropyridine-3-carboxylic acid (CAS 787640-16-8)
- 5α-Androstan-3β-ol (CAS 1224-92-6)
- N-Methyl-1-phenyl-3-(pyrrolidin-1-yl)propan-1-amine (CAS 672310-28-0)
- 5'-Bromospiro[imidazolidine-4,1'-[1H]indene]-2,3',5(2'H)-trione (CAS 1889290-24-7)
- 1-phenyl-3-piperidin-4-ylurea (CAS 61220-48-2)
- (2S)-2-Amino-N-((1-benzylpyrrolidin-3-yl)methyl)-N,3-dimethylbutanamide (CAS 1354026-64-4)
- (3-Cyano-4-cyclopropylphenyl)boronic acid (CAS 2225169-09-3)
- 4-Chloro-5-(trifluoromethoxy)pyrimidine (CAS 1261629-90-6)
- Mast Cell Degranulating Peptide HR-1 (CAS 80533-94-4)
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