tert-Butyl 4-(5-cyano-4-methylpyridin-2-yl)piperazine-1-carboxylate CAS 1355227-43-8
| CAS No. | 1355227-43-8 |
| Molecular Formula | C16H22N4O2 |
| Molecular Weight | 302.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
tert-Butyl 4-(5-cyano-4-methylpyridin-2-yl)piperazine-1-carboxylate (CAS 1355227-43-8), molecular formula C16H22N4O2 and molecular weight 302.37 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, tert-Butyl 4-(5-cyano-4-methylpyridin-2-yl)piperazine-1-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 302.37 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures tert-Butyl 4-(5-cyano-4-methylpyridin-2-yl)piperazine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H22N4O2 |
| Molecular Weight | 302.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 4 |
Recommended Standards
- tert-Butyl 4-(5-cyano-6-methylpyridin-2-yl)piperazine-1-carboxylate (CAS 1355224-36-0)
- (4-Methyl-6-(methyl(phenyl)amino)pyridin-3-yl)(phenyl)methanone (CAS 1355230-94-2)
- (6-(Indolin-1-yl)pyridin-3-yl)(phenyl)methanol (CAS 1355219-50-9)
- Phenyl(2-(quinolin-6-yl)pyrrolidin-1-yl)methanone (CAS 1355231-06-9)
- Methyl 3,4-O-Isopropylidene-α-D-galactopyranoside (CAS 40269-01-0)
- 2-(Difluoromethyl)-5-nitro-6-(trifluoromethoxy)pyridine-3-carbonyl chloride (CAS 1805090-82-7)
- 4-Decanoyl-3-methyl-1-phenyl-1H-pyrazol-5(4H)-one (CAS 18199-28-5)
- 2-Amino-3-bromobenzenesulfonamide (CAS 339365-12-7)
- N,N-Diethyl-4-(1-phenyl-4,5-dihydro-1H-pyrazol-3-yl)aniline (CAS 82437-47-6)
- 1,1,3,5,7,9,10-Heptachloro-1,2,2,3,4,4,5,6,6,7,8,8,9,10,10-pentadecafluorodecane (CAS 307-41-5)
- 3-Cyclobutoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1257553-86-8)
- 2-bromo-1-(5-hydroxy-2-pyridyl)ethanone (CAS 1346532-82-8)
- 1-Chloro-3-methyl-2-(2-methylallyl)benzene (CAS 951895-37-7)
- MCH-Gene-Overprinted-Polypeptide-14 (rat) (H-4746.0500) (CAS 182917-44-8)
Why CATO?
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