1355334-57-4 2-[2,5-Bis(trifluoromethyl)phenyl]-ethanimidamide hydrochloride CAS 1355334-57-4
| CAS No. | 1355334-57-4 |
| Molecular Formula | C10H8F6N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1355334-57-4 2-[2,5-Bis(trifluoromethyl)phenyl]-ethanimidamide hydrochloride (C10H8F6N2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
1355334-57-4 2-[2,5-Bis(trifluoromethyl)phenyl]-ethanimidamide hydrochloride (CAS 1355334-57-4), molecular formula C10H8F6N2HCl and molecular weight 306.63 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8F6N2 HCl |
| Molecular Weight | 306.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Bis Standards
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidin-3-ol hydrochloride (CAS 1000198-74-2)
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidine (CAS 1000198-76-4)
- (2-Methyl-4-(trifluoromethyl)thiazol-5-yl)methanol (CAS 1000339-72-9)
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- 2-(4-(trifluoromethyl)piperidin-1-yl)thiazole-5-carbaldehyde (CAS 1000339-88-7)
- 3-(2-(4-(trifluoromethyl)piperidin-1-yl)ethyl)benzaldehyde (CAS 1000339-89-8)
- 4-(2-(4-(trifluoromethyl)piperidin-1-yl)acetyl)-1H-pyrrole-2-carbaldehyde (CAS 1000339-90-1)
Recommended Standards
- 2-Amino-6-methyl-4-nitrophenol (CAS 6265-03-8)
- tert-Butyl 2-(5-bromopyridin-2-yl)-2-cyanoacetate (CAS 1279820-53-9)
- (R)-2-Methyl-1-[(S)-1-phenylethyl]-4-piperidone (CAS 89467-37-8)
- 4-((4-Nitrophenoxy)methyl)benzohydrazide (CAS 379254-49-6)
- 4-chloropyrrolo[2,1-f][1,2,4]triazine-7-carbaldehyde (CAS 1546505-09-2)
- 5-Phenyl-1H-pyrrolo[2,3-b]pyridin-2(3H)-one (CAS 223646-08-0)
- N-[Bis(aziridin-1-yl)phosphoryl]-4-fluoro-benzamide (CAS 726-92-1)
- Pitavastatin Impurity 119 (CAS CATO-C4X-1037119)
- 3-Ethyl-2-fluoropyridine (CAS 1020718-14-2)
- Human IgE Pentapeptide HEPP (CAS 62087-72-3)
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