1-(4-Bromophenyl)-3-(2-chloroacetyl)urea CAS 13558-79-7
| CAS No. | 13558-79-7 |
| Molecular Formula | C9H8BrClN2O2 |
| Molecular Weight | 291.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-Bromophenyl)-3-(2-chloroacetyl)urea.
1-(4-Bromophenyl)-3-(2-chloroacetyl)urea (CAS 13558-79-7), molecular formula C9H8BrClN2O2 and molecular weight 291.53 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(4-Bromophenyl)-3-(2-chloroacetyl)urea (C9H8BrClN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H8BrClN2O2 |
| Molecular Weight | 291.53 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromophenyl Standards
- 2-bromophenyl 3-chloro-2,2-dimethylpropanoate (CAS 106141-11-1)
- [(4-bromophenyl)(pyridin-3-yl)methyl](ethyl)amine (CAS 1153742-21-2)
- 1-(4-Bromophenyl)-N-(pyridin-3-ylmethyl)ethan-1-amine (CAS 353235-89-9)
- (3-Bromophenyl)(3,5-dimethylphenyl)methanol (CAS 1178484-59-7)
- 1-(3-Bromophenyl)-2-phenylpropan-2-ol (CAS 1179208-30-0)
- (2-Bromophenyl)(2,4-dimethylphenyl)methanol (CAS 1281267-23-9)
- (2-Bromophenyl)(3,5-dimethylphenyl)methanol (CAS 1281603-13-1)
- (3-Bromophenyl)(2,5-dimethylphenyl)methanol (CAS 1282062-71-8)
Recommended Standards
- Octadecanoic-16,16,17,17,18,18,18-d7 Acid (CAS 951209-59-9)
- 6-Bromo-8-chloro-3,3-dimethyl-2,3-dihydroimidazo[1,5-a]pyridine-1,5-dione (CAS 1849592-09-1)
- 2,3,6-Trichloro-N-(1H-1,2,4-triazol-5-yl)benzamide (CAS 302804-90-6)
- (E)-3-(5-bromo-3-chloro-2-methoxyphenyl)acrylic acid (CAS 518023-87-5)
- methyl 2-iodo-1-methyl-1H-imidazole-5-carboxylate (CAS 1955557-31-9)
- 2-(Bromodifluoromethyl)-5-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 1353778-41-2)
- Acrylic Acid-Ethyl Ester (CAS 140-88-5)
- 4-(4-Methylpyrimidin-2-yl)aniline (CAS 474397-16-5)
- 4-((5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)methyl)morpholine hydrochloride (CAS 2377607-99-1)
- 1-(4-Methoxyphenethyl)-4-aminopiperidine 1-[2-(4-Methoxyphenyl)ethyl]-4-aminopiperidine 4-Amino-1-(4-methoxyphenethyl)piperidine 4-Amino-1-[2-(4-methoxyphenyl)ethyl]piperidine 85098-70-0 A1618 (CAS 85098-70-0)
- N'-((Dimethylamino)methylene)-N,N-dimethylformohydrazonamide hydrochloride (CAS 124355-27-7)
- 7-Amino-4-chloropyrido[2,3-d]pyrimidine (CAS 1423034-11-0)
- 1-(4-Flourobenzenesulfonyl)-3-(1,3-dioxolynyl)-5-methyl-1,3-dihydro-2H-indol-2-one (CAS 866152-08-1)
- Anti-Inflammatory Peptide 3 (CAS 118850-73-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com