(3-Hydroxypiperidin-1-yl)(5-iodothiophen-3-yl)methanone CAS 1355935-33-9
| CAS No. | 1355935-33-9 |
| Molecular Formula | C10H12INO2S |
| Molecular Weight | 337.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (3-Hydroxypiperidin-1-yl)(5-iodothiophen-3-yl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(3-Hydroxypiperidin-1-yl)(5-iodothiophen-3-yl)methanone (CAS 1355935-33-9) is a high-purity analytical reference standard with the molecular formula C10H12INO2S and a molecular weight of 337.18 g/mol.
The molecular framework of (3-Hydroxypiperidin-1-yl)(5-iodothiophen-3-yl)methanone (C10H12INO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H12INO2S |
| Molecular Weight | 337.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Hydroxypiperidin Standards
- Ethyl 3-(4-(2-(4-hydroxypiperidin-1-yl)acetamido)phenyl)acrylate (CAS 1050533-40-8)
- 3-(3-((4-Hydroxypiperidin-1-yl)sulfonyl)-4-methoxyphenyl)propanoic acid (CAS 1708301-13-6)
- (4-Benzyl-4-hydroxypiperidin-1-yl)(5-nitrofuran-2-yl)methanone (CAS 831203-95-3)
- 10-((4-Hydroxypiperidin-1-yl)methyl)chromeno[4,3,2-de]phthalazin-3(2H)-one (CAS 902128-92-1)
- [[2-(4-Hydroxypiperidin-1-yl)-2-oxoethyl]-(4-methoxyphenyl)amino]acetic acid (CAS 1142205-76-2)
- 6-((4-Hydroxypiperidin-1-yl)sulfonyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 317329-46-7)
- 3-(1-Benzyl-4-hydroxypiperidin-4-yl)-2-chloroquinoline (CAS 783368-13-8)
- 2-(2-(4-Hydroxypiperidin-1-yl)-1H-benzo[d]imidazol-1-yl)nicotinonitrile (CAS 1314356-29-0)
Recommended Standards
- 2-(3-Bromo-4-fluorophenyl)-1-(4-methoxy-3-methylphenyl)ethan-1-one (CAS 1209495-16-8)
- Ethyl 3-chloro-6-(chlorosulfonyl)-1-methyl-1h-pyrrolo[3,2-b]pyridine-2-carboxylate (CAS 1423025-12-0)
- B-[9-(1-Naphthalenyl)-9H-carbazol-3-yl]boronic acid (CAS 1133057-97-2)
- 2-(4-Iodobenzyl)isothiazolidine 1,1-dioxide (CAS 1436243-36-5)
- 3-Acetyl-4-hydroxy-1H-pyrrole-2,5-dione (CAS 72543-14-7)
- 2-Bromo-4-nitropyridine (CAS 6945-67-1)
- 5-(4-(Bis(4-bromophenyl)amino)styryl)thiophene-2-carbaldehyde (CAS 1190764-15-8)
- N-(5-Nitro-1H-1,2,4-triazol-3-yl)acetamide (CAS 3572-23-4)
- 1H-Imidazole-4-methanol 1H-imidazol-4-ylmethanol 4-(Hydroxymethyl)imidazole 822-55-9 CHEBI:28182 imidazole-4-methanol (CAS 822-55-9)
- 5-Amino-2-hydroxybenzenesulfonic acid (CAS 2835-04-3)
- Dapagliflozin Impurity 11 (CAS 333361-51-6)
- 70381-92-9 3,4-Dihydro-2H-pyrano[3,2-b]pyridine DTXSID50500040 (CAS 70381-92-9)
- 2-Bromo-5-fluoro-N-(thiazol-2-yl)benzamide (CAS 1016732-03-8)
- (Glu1)-Fibrinopeptide B (human) (CAS 103213-49-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com