3-Chloro-6-methoxy-1H-indazol-5-amine CAS 1356017-73-6
| CAS No. | 1356017-73-6 |
| Molecular Formula | C8H8ClN3O |
| Molecular Weight | 197.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 197.62 g/mol gives 3-Chloro-6-methoxy-1H-indazol-5-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-Chloro-6-methoxy-1H-indazol-5-amine (CAS 1356017-73-6), a certified reference material (molecular formula C8H8ClN3O, MW 197.62 g/mol) for analytical method development and quality control.
Structurally, 3-Chloro-6-methoxy-1H-indazol-5-amine (C8H8ClN3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 197.62 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8ClN3O |
| Molecular Weight | 197.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 1-((4-Chloro-1H-pyrazol-1-yl)methyl)-1H-pyrazol-3-amine (CAS 1006472-82-7)
- 2-(4-Chloro-3-methyl-phenoxy)-butyric acid (CAS 1006483-33-5)
- 2-(6-Chloro-9h-purin-9-yl)ethan-1-amine (CAS 100690-26-4)
- 2-Chloro-n,n-dimethyl-7h-purin-6-amine (CAS 100960-20-1)
- 2-Chloro-N-ethyl-9H-purin-6-amine (CAS 102429-99-2)
- 2-Chloro-5-cyclopropylpyridine-3-carboxylic acid (CAS 1035690-32-4)
- 5-Chloro-4-methyl-1H-pyrazolo[3,4-b]pyridine-3,6-diamine (CAS 107450-28-2)
- 5-Chloro-2,3-dihydro-6-methoxy-1h-isoindol-1-one (CAS 1138220-79-7)
Recommended Standards
- 7-Chloro-6-hydroxy-5-methylisoindolin-1-one (CAS 1353878-10-0)
- Methyl 6-chloro-5-vinylnicotinate (CAS 1360884-13-4)
- 5-Chloro-4-ethoxy-2-hydroxybenzonitrile (CAS 1352494-16-6)
- 7-Chloro-4-methoxyindolin-2-one (CAS 1368597-34-5)
- Tert-butyl 4-(benzyloxy)-3-oxobutanoate (CAS 95967-46-7)
- (S)-5-Isopropyl-3-methyloxazolidin-4-one (CAS 89053-46-3)
- Methyl 3-(8-azaspiro[4.5]Decan-2-yl)propanoate (CAS 1638760-81-2)
- (2-(2-Bromophenyl)oxazol-4-yl)methanol (CAS 885274-02-2)
- n-Isopropyl-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine (CAS 63895-01-2)
- 4-Benzyloxygramine (CAS 13523-95-0)
- Perospirone Impurity 13 (CAS CATO-C4X-245813)
- N-Propyl-1H-indazol-5-amine (CAS 1156206-70-0)
- 3-Fluoro-2-(2-fluorophenyl)-6-(trifluoromethyl)pyridine (CAS 1214329-02-8)
- Semaglutide Impurity 139 (CAS CATO-C4X-2226139)
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