2,3-Bis(chloromethyl)-6-(trifluoromethyl)pyridine CAS 1356110-02-5
| CAS No. | 1356110-02-5 |
| Molecular Formula | C8H6Cl2F3N |
| Molecular Weight | 244.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2,3-Bis(chloromethyl)-6-(trifluoromethyl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2,3-Bis(chloromethyl)-6-(trifluoromethyl)pyridine (CAS 1356110-02-5) is a high-purity analytical reference standard with the molecular formula C8H6Cl2F3N and a molecular weight of 244.04 g/mol.
2,3-Bis(chloromethyl)-6-(trifluoromethyl)pyridine (C8H6Cl2F3N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H6Cl2F3N |
| Molecular Weight | 244.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Bis Standards
- 2-(Chloromethyl)-4-(2-chlorophenyl)-1,3-thiazole (CAS 1211510-85-8)
- 2-(Chloromethyl)-4-(3-chlorophenyl)-1,3-thiazole (CAS 1342394-08-4)
- 4-(Chloromethyl)-2-(4-chlorophenyl)-1,3-thiazole (CAS 17969-22-1)
- 4-(Chloromethyl)-2-(2-chlorophenyl)thiazole (CAS 588676-51-1)
- 4-(Chloromethyl)-2-(3-chlorophenyl)thiazole (CAS 97992-66-0)
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- 4-((Chloromethyl)sulfonyl)-2,2-dimethylthiomorpholine (CAS 1602008-97-8)
- 1-benzyl-3-(chloromethyl)pyrrolidine-3-carbaldehyde (CAS 2654084-04-3)
Recommended Standards
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- 6-Iodo-2-thioxo-3-(m-tolyl)-2,3-dihydroquinazolin-4(1H)-one (CAS 18741-40-7)
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