4-Fluorocinnamoyl chloride CAS 13565-08-7
| CAS No. | 13565-08-7 |
| Molecular Formula | C9H6ClFO |
| Molecular Weight | 184.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-Fluorocinnamoyl chloride (CAS 13565-08-7) is a high-purity analytical reference standard with the molecular formula C9H6ClFO and a molecular weight of 184.59 g/mol.
4-Fluorocinnamoyl chloride (C9H6ClFO) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 4-Fluorocinnamoyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H6ClFO |
| Molecular Weight | 184.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Halogen Content | F/Cl-containing |
Recommended Standards
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- 4-Chloro-7-fluoro-2,3-dihydro-1H-inden-1-one (CAS 1260018-63-0)
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- 2-[(3-Chloro-2-fluorophenyl)methoxy]-2,3-dihydro-1H-isoindole-1,3-dione (CAS 321430-44-8)
- 4-(2-Naphthyl)phenylboronic Acid Pinacol Ester (CAS 1092390-02-7)
- 6-(1H-Indol-1-yl)pyridazin-3(2H)-one (CAS 109890-29-1)
- 4,6-dichloro-5-nitronicotinic acid (CAS 1192263-83-4)
- Lysine Impurity 39 (CAS 94613-75-9)
- 2-Bromo-6-((1-isopropylpyrrolidin-3-yl)methyl)pyridine (CAS 1316222-77-1)
- Bosentan impurity 17 (CAS CATO-C4X-156417)
- Semaglutide Impurity 148 (CAS CATO-C4X-2226148)
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