3-[2-(trifluoromethyl)phenyl]but-2-enoic acid CAS 1356809-47-6
| CAS No. | 1356809-47-6 |
| Molecular Formula | C11H9F3O2 |
| Molecular Weight | 230.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-[2-(trifluoromethyl)phenyl]but-2-enoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-[2-(trifluoromethyl)phenyl]but-2-enoic acid (CAS 1356809-47-6) is a high-purity analytical reference standard with the molecular formula C11H9F3O2 and a molecular weight of 230.18 g/mol.
3-[2-(trifluoromethyl)phenyl]but-2-enoic acid (C11H9F3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H9F3O2 |
| Molecular Weight | 230.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
Related trifluoromethyl Standards
- 2-Methyl-3-(trifluoromethyl)cinnamic acid (CAS 1017777-95-5)
- 5-Methyl-2-(trifluoromethyl)cinnamic acid (CAS 1017779-24-6)
- 1-[3-(Trifluoromethyl)phenyl]cyclopropanecarboxylic Acid (CAS 104173-41-3)
- 3-Methyl-5-(trifluoromethyl)cinnamic acid (CAS 1092460-62-2)
- Benzyl 2-(trifluoromethyl)acrylate (CAS 111339-17-4)
- 2-[2-(Trifluoromethyl)phenyl]cyclopropanecarboxylic Acid (CAS 1187933-13-6)
- 3-[3-methyl-4-(trifluoromethyl)phenyl]prop-2-enoic acid (CAS 1214790-35-8)
- 3-[2-methyl-4-(trifluoromethyl)phenyl]prop-2-enoic acid (CAS 1214790-49-4)
Recommended Standards
- 4-(2-(Trifluoromethoxy)phenyl)but-3-en-2-one (CAS 1344879-50-0)
- 4-((1R,2R)-2-(trifluoromethyl)cyclopropyl)benzoic acid (CAS 1404192-14-8)
- 2-Bromo-4-(trimethylsilyl)pyridine (CAS 134391-66-5)
- 3-((1S,2S)-2-(trifluoromethyl)cyclopropyl)benzoic acid (CAS 1404192-15-9)
- n-(4-Aminophenyl)-1-methyl-1h-pyrazole-3-carboxamide (CAS 957514-02-2)
- 2-(Difluoromethyl)-4-iodo-6-methoxypyridine-3-acetic acid (CAS 1806885-09-5)
- (Z)-N'-[6-Oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-2-yl]{[(3-methoxyphenyl)methyl]sulfanyl}methanimidamide (CAS 866142-62-3)
- 5-(3-Amino-1h-pyrazol-1-yl)pentan-1-ol (CAS 1251277-04-9)
- Methyl-4-hydroxy-2-methoxynicotinate (CAS 1190322-55-4)
- 1-(4-(Benzyloxy)phenyl)propan-2-one (CAS 5586-92-5)
- tert-Butyl 2-(1-aminoethyl)-1H-indole-1-carboxylate (CAS 1779122-88-1)
- 2-(4-Fluorophenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole (CAS 111883-62-6)
- 2-Isopropyl-6-(trifluoromethyl)morpholine-3-thione (CAS 1375472-25-5)
- Semaglutide impurity 270 (CAS CATO-C4X-2226270)
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