N-Fmoc-L-threonine (2-Tolyl-2-oxo-ethyl)ester CAS 1356841-91-2
| CAS No. | 1356841-91-2 |
| Molecular Formula | C28H27NO6 |
| Molecular Weight | 473.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
N-Fmoc-L-threonine (2-Tolyl-2-oxo-ethyl)ester (CAS 1356841-91-2) is a high-purity analytical reference standard with the molecular formula C28H27NO6 and a molecular weight of 473.52 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, N-Fmoc-L-threonine (2-Tolyl-2-oxo-ethyl)ester is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 473.52 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H27NO6 |
| Molecular Weight | 473.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
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