1-aminomethyl-8-aZa-spiro[4.5]decane-8-carboxylic acid tert-butyl ester CAS 1357352-01-2
| CAS No. | 1357352-01-2 |
| Molecular Formula | C15H28N2O2 |
| Molecular Weight | 268.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-aminomethyl-8-aZa-spiro[4.5]decane-8-carboxylic acid tert-butyl ester (CAS 1357352-01-2), molecular formula C15H28N2O2 and molecular weight 268.40 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-aminomethyl-8-aZa-spiro[4.5]decane-8-carboxylic acid tert-butyl ester (C15H28N2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 1-aminomethyl-8-aZa-spiro[4.5]decane-8-carboxylic acid tert-butyl ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H28N2O2 |
| Molecular Weight | 268.40 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
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Recommended Standards
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