tert-Butyl 5-(fluoromethyl)-2,7-diazaspiro[3.5]nonane-2-carboxylate CAS 1357353-43-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1357353-43-5
Molecular FormulaC13H23FN2O2
Molecular Weight258.33 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

tert-Butyl 5-(fluoromethyl)-2,7-diazaspiro[3.5]nonane-2-carboxylate CAS 1357353-43-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 258.33 g/mol gives tert-Butyl 5-(fluoromethyl)-2,7-diazaspiro[3.5]nonane-2-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

tert-Butyl 5-(fluoromethyl)-2,7-diazaspiro[3.5]nonane-2-carboxylate (CAS 1357353-43-5), molecular formula C13H23FN2O2 and molecular weight 258.33 g/mol, is a CATO reference standard with documented purity and traceability.

tert-Butyl 5-(fluoromethyl)-2,7-diazaspiro[3.5]nonane-2-carboxylate (C13H23FN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC13H23FN2O2
Molecular Weight258.33 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1991
Halogen ContentF-containing
Nitrogen Atoms2

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