Clopidogrel Impurity 6 CAS 1357474-92-0
| CAS No. | 1357474-92-0 |
| Molecular Formula | C17H18ClNO2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Clopidogrel Impurity 6 (CAS 1357474-92-0) is a certified pharmaceutical impurity reference standard with the molecular formula C17H18ClNO2SH2O4S and a molecular weight of 433.92 g/mol.
Structurally, Clopidogrel Impurity 6 (C17H18ClNO2SH2O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 433.92 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Clopidogrel Impurity 6 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H18ClNO2S H2O4S |
| Molecular Weight | 433.92 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Clopidogrel Standards
- Clopidogrel Impurity 74 (CAS 1008008-56-7)
- Clopidogrel Impurity 82 (CAS 1015247-87-6)
- rac-Clopidogrel EP Impurity A HCl (CAS 1015247-88-7)
- rac Clopidogrel [(tert-Butylcarbonyl)oxy]methyl ester (CAS 1043913-82-1)
- 2-Oxo Clopidogrel (Mixture of Diastereomers) (CAS 109904-27-0)
- Clopidogrel Impurity 42 (CAS 109904-36-1)
- cis-Clopidogrel glutathione disulfide, mixture of diastereomers (CAS 1118605-95-0)
- Clopidogrel Impurity 48 (CAS 111954-31-5)
Recommended Standards
- Obeticholic Acid Impurity 8 (CAS 1908444-28-9)
- Pirfenidone Impurity 31 (CAS 13179-27-6)
- Canagliflozin Impurity 60 (CAS CATO-C4X-112360)
- (Z)-2-((3S,4R,5R)-3,5-bis((tert-Butyldimethylsilyl)oxy)-4-(3-((tert-butyldimethylsilyl)oxy)propoxy)-2-methylenecyclohexylidene)ethan-1-ol (CAS 200636-46-0)
- 1,3-Bis-(1-benzyl-4-trifluoromethyl-piperidin-4-yl)-urea (CAS 2097068-72-7)
- Tert-butyl (4-(6-chloropyridin-3-yl)-4-oxobutyl)carbamate (CAS 1352516-72-3)
- 2-(Bromomethyl)-5-(difluoromethyl)-3-fluoro-6-methoxypyridine (CAS 1806929-67-8)
- 1-(4-Ethyl-3,5-dimethyl-2H-pyrrol-2-ylidene)ethanol (CAS 750511-61-6)
- (2-((3,5-Difluorophenoxy)methyl)phenyl)boronic acid (CAS 1218790-92-1)
- Semaglutide impurity 248 (CAS CATO-C4X-2226248)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com