Thiazolo[4,5-b]pyridin-2-amine CAS 13575-41-2
| CAS No. | 13575-41-2 |
| Molecular Formula | C6H5N3S |
| Molecular Weight | 151.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Thiazolo[4,5-b]pyridin-2-amine (CAS 13575-41-2), molecular formula C6H5N3S and molecular weight 151.19 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrile group, sulfur-containing functionality, an aromatic ring system, Thiazolo[4,5-b]pyridin-2-amine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 151.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H5N3S |
| Molecular Weight | 151.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Thiazolo Standards
- Thiazolo[5,4-c]pyridin-2-amine (CAS 108310-79-8)
- Thiazolo[5,4-c]pyridin-4-amine (CAS 1221278-82-5)
- [1,2]thiazolo[3,4-b]pyridin-3-amine (CAS 42242-06-8)
- Thiazolo[3,2-a]pyridin-4-ium-3-olate (CAS 42715-25-3)
- Thiazolo[4,5-c]pyridin-2-amine (CAS 89786-54-9)
- Thiazolo[5,4-b]pyridin-6-amine (CAS 948306-28-3)
- Thiazolo[4,5-c]pyridin-4(5H)-one (CAS 1208988-80-0)
- Thiazolo[4,5-b]pyridin-2(3H)-one (CAS 152170-29-1)
Recommended Standards
- 5-Methylthiazolo[5,4-d]pyrimidine (CAS 13554-89-7)
- 4-Amino-1,2,3-benzothiadiazole (CAS 13599-80-9)
- 2-Methylthiazolo[5,4-d]pyrimidine (CAS 13554-88-6)
- 6-Hydroxybenzothiazole (CAS 13599-84-3)
- N-(Pyridin-3-yl)acridin-9-amine (CAS 75775-64-3)
- 1-(4-Chloro-2-nitrophenyl)azetidine-3-carboxylic acid (CAS 1187929-02-7)
- N-Isobutyl-2-(naphthalen-2-yloxy)acetamide (CAS 391229-13-3)
- 2,2,2-Trifluoroethyl vinyl ether (CAS 406-90-6)
- Salbutamol Impurity 90 (CAS CATO-C4X-117690)
- Relebactam Impurity 68 (CAS CATO-C4X-214468)
- Methyl (3-hydroxy-1,2-dihydroquinoxaline-1-carbonyl)-L-leucinate (CAS 1173678-35-7)
- Carbetocin Impurity 38 (CAS CATO-C4X-191138)
- 3,5-Dibromo-4-methyl-(1H)indazole (CAS 1082040-13-8)
- Allo-D-Ile12-Tirzepatide (CAS CATO-CPTD788963)
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