3-chloro-1H-pyrazolo[4,3-b]pyridine CAS 1357945-31-3
| CAS No. | 1357945-31-3 |
| Molecular Formula | C6H12ClN3 |
| Molecular Weight | 161.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-chloro-1H-pyrazolo[4,3-b]pyridine.
3-chloro-1H-pyrazolo[4,3-b]pyridine (CAS 1357945-31-3), molecular formula C6H12ClN3 and molecular weight 161.63 g/mol, is a CATO reference standard with documented purity and traceability.
3-chloro-1H-pyrazolo[4,3-b]pyridine (C6H12ClN3) contains a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H12ClN3 |
| Molecular Weight | 161.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related chloro Standards
- 2-chloro-N-cyclopropyl-N-ethylacetamide (CAS 1087792-38-8)
- 2-chloro-N-(cyclobutylmethyl)acetamide (CAS 1095592-81-6)
- 3-Chloro-1H-pyrazolo[3,4-b]pyridine (CAS 117007-51-9)
- 2-chloro-N-(cyclopropylmethyl)-N-methylacetamide (CAS 1178287-38-1)
- 2-Chloro-N-(1-methylcyclobutyl)acetamide (CAS 1211496-15-9)
- 2-Chloro-N-cyclopentylacetamide (CAS 125674-23-9)
- 6-chloro-1H-pyrazolo[4,3-b]pyridine (CAS 1260670-01-6)
- 4-chloro-1h-pyrazolo[3,4-c]pyridine (CAS 1260671-36-0)
Recommended Standards
- (S)-1-(3-Chloropiperidin-1-yl)ethanone (CAS 1353997-31-5)
- 7-chloro-1H-pyrazolo[4,3-c]pyridine (CAS 1357946-01-0)
- (R)-1-(3-Chloropiperidin-1-yl)ethanone (CAS 1353997-13-3)
- 2-chloropyrrolo[2,1-f][1,2,4]triazine (CAS 1363383-25-8)
- Enkephalin(1-3) (CAS 21778-69-8)
- Benzyl 4-amino-8,9-dihydro-5H-pyrimido[4,5-d]azepine-7(6H)-carboxylate (CAS 1260810-71-6)
- N-(5-(4-Chlorophenyl)-1,3,4-thiadiazol-2-yl)-2-(phenylthio)butanamide (CAS 394237-13-9)
- 2-Bromo-1-(2,3-dihydrobenzofuran-5-yl)ethanone (CAS 151427-19-9)
- 1-(Piperidin-2-ylmethyl)urea (CAS 955381-41-6)
- 3-Phenoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1309981-45-0)
- 2-(Isobutylthio)-1H-benzimidazole (CAS 75080-14-7)
- 1-Butyl-6-methylcyclohex-1-ene (CAS 61685-33-4)
- 5-(trifluoromethyl)cyclohexane-1,3-dione (CAS 124612-15-3)
- Semaglutide impurity 32 (CAS CATO-C4X-222632)
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