7-Chloroimidazo[1,2-a]pyridin-8-amine CAS 1357946-45-2
| CAS No. | 1357946-45-2 |
| Molecular Formula | C7H6ClN3 |
| Molecular Weight | 167.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 167.60 g/mol gives 7-Chloroimidazo[1,2-a]pyridin-8-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
7-Chloroimidazo[1,2-a]pyridin-8-amine (CAS 1357946-45-2) is a high-purity analytical reference standard with the molecular formula C7H6ClN3 and a molecular weight of 167.60 g/mol.
Structurally, 7-Chloroimidazo[1,2-a]pyridin-8-amine (C7H6ClN3) contains a nitrile group, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 167.60 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-Chloroimidazo[1,2-a]pyridin-8-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H6ClN3 |
| Molecular Weight | 167.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloroimidazo Standards
- 7-Chloroimidazo[1,2-a]pyridin-3-amine (CAS 1289083-20-0)
- 5-Chloroimidazo[1,2-a]pyridin-8-amine (CAS 1357947-17-1)
- 6-Chloroimidazo[1,2-a]pyridin-5-amine (CAS 1378670-84-8)
- 7-Chloroimidazo[1,2-a]pyridin-2-amine (CAS 1501148-82-8)
- 5-Chloroimidazo[1,2-a]pyridin-2-amine (CAS 1504961-12-9)
- 1-Chloroimidazo[1,5-a]pyridin-7-amine (CAS 1556312-61-8)
- 3-Chloroimidazo[1,2-a]pyridin-8-amine (CAS 177556-54-6)
- 5-Chloroimidazo[1,2-a]pyridin-3-amine (CAS 82193-23-5)
Recommended Standards
- 1352881-33-4 2-Chloro-7-methylimidazo-[1,5-b]pyridazine (CAS 1352881-33-4)
- 5-Chloro-3-methyl-2H-pyrazolo[3,4-b]pyridine (CAS 1352397-08-0)
- 6-Amino-4-chloro-2-methylnicotinonitrile (CAS 1357956-90-1)
- 8-Chloro-1-methylimidazo[1,5-a]pyrazine (CAS 1340877-38-4)
- 2,2,2-Trifluoro-1-(piperidin-2-yl)ethan-1-ol (CAS 1258651-25-0)
- (E)-3-(4-(Benzyloxy)phenyl)-2-ethoxyacrylic acid (CAS 1017789-28-4)
- 6-Phenylhexanamide (CAS 31274-14-3)
- Sugiol (CAS 511-05-7)
- 22-NHC hydrochloride (CAS 360068-87-7)
- 3-Fluoro-N-(imidazo[1,2-a]pyridin-2-ylmethyl)-4-methylaniline (CAS 1020955-83-2)
- 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(3-fluorophenyl)urea (CAS 1024270-20-9)
- 4-(1-Phenyl-1H-benzo[d]imidazol-2-yl)aniline (CAS 65847-34-9)
- (2R,3S,4S,5R,6S)-2-(acetoxymethyl)-6-(((2R,3R,4S,5R,6R)-4,5-diacetoxy-2-(acetoxymethyl)-6-bromotetrahydro-2H-pyran-3-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate (CAS 4753-07-5)
- Semaglutide impurity 54 (CAS CATO-C4X-222654)
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