3-Bromo-6-chloro-1H-pyrazolo[3,4-b]pyridine CAS 1357946-70-3
| CAS No. | 1357946-70-3 |
| Molecular Formula | C6H3BrClN3 |
| Molecular Weight | 232.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Bromo-6-chloro-1H-pyrazolo[3,4-b]pyridine is closely related to a nitrile group, chlorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Bromo-6-chloro-1H-pyrazolo[3,4-b]pyridine (CAS 1357946-70-3) is a high-purity analytical reference standard with the molecular formula C6H3BrClN3 and a molecular weight of 232.47 g/mol.
Based on its molecular formula C6H3BrClN3, 3-Bromo-6-chloro-1H-pyrazolo[3,4-b]pyridine contains a nitrile group, chlorine/bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 232.47 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H3BrClN3 |
| Molecular Weight | 232.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
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