1-(4-Fluorophenyl)-6-methoxy-4-oxo-n-(oxolan-2-ylmethyl)-1,4-dihydropyridazine-3-carboxamide CAS 1358366-99-0
| CAS No. | 1358366-99-0 |
| Molecular Formula | C17H18FN3O4 |
| Molecular Weight | 347.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-(4-Fluorophenyl)-6-methoxy-4-oxo-n-(oxolan-2-ylmethyl)-1,4-dihydropyridazine-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-(4-Fluorophenyl)-6-methoxy-4-oxo-n-(oxolan-2-ylmethyl)-1,4-dihydropyridazine-3-carboxamide (CAS 1358366-99-0), molecular formula C17H18FN3O4 and molecular weight 347.34 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(4-Fluorophenyl)-6-methoxy-4-oxo-n-(oxolan-2-ylmethyl)-1,4-dihydropyridazine-3-carboxamide (C17H18FN3O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C17H18FN3O4 |
| Molecular Weight | 347.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluorophenyl Standards
- Methyl 1-(4-fluorophenyl)-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011398-72-3)
- 1-(4-Fluorophenyl)-3-methyl-6-phenyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011399-41-9)
- Methyl 1-(2-fluorophenyl)-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011399-45-3)
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- 1-(2-fluorophenyl)-6-(4-methylphenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011399-69-1)
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Recommended Standards
- Methyl 4-[[2-(Methoxycarbonyl)phenyl]thio]-3-nitrobenzoate (CAS 1319194-13-2)
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- 3,4-Dihydroxy-N,N-dimethyl-9,10-dioxo-9,10-dihydroanthracene-2-sulfonamide (CAS 1313738-84-9)
- 1-(3-fluorobenzyl)-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 867329-86-0)
- 4,4'-((1E,1'E)-[2,2'-Bipyridine]-4,4'-diylbis(ethene-2,1-diyl))bis(N,N-dimethylaniline) (CAS 166827-54-9)
- Cyclopropyl(4-isopropylphenyl)methanamine (CAS 535925-87-2)
- Triazophos,Dichlorvos,Methamidophos,Acephate (CAS CATO-CCRM104023)
- (2E)-2-(Phenylmethylidene)cyclobutan-1-one (CAS 208652-65-7)
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- n1-Methylcyclopentane-1,3-diamine (CAS 1510453-97-0)
- Ethyl (2Z,4Z)-2-cyano-3-hydroxy-5-phenyl-4-(phenylformamido)penta-2,4-dienoate (CAS 75989-96-7)
- 2-Methoxy-5-((((5-methylisoxazol-3-yl)methyl)amino)methyl)phenol (CAS 1241160-62-2)
- Tirzepatide Impurity 48 (CAS CATO-C4X-324048)
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