N,N-Dimethyl-4-(piperidin-3-ylmethyl)pyrimidin-2-amine CAS 1359705-77-3
| CAS No. | 1359705-77-3 |
| Molecular Formula | C12H20N4 |
| Molecular Weight | 220.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
N,N-Dimethyl-4-(piperidin-3-ylmethyl)pyrimidin-2-amine (CAS 1359705-77-3), molecular formula C12H20N4 and molecular weight 220.31 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N,N-Dimethyl-4-(piperidin-3-ylmethyl)pyrimidin-2-amine (C12H20N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), N,N-Dimethyl-4-(piperidin-3-ylmethyl)pyrimidin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H20N4 |
| Molecular Weight | 220.31 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 4 |
Recommended Standards
- 4-Methyl-6-(4-methylazepan-1-yl)pyrimidin-2-amine (CAS 1355871-53-2)
- 3-Methyl-2-(2,4,5-trimethylphenyl)butanoic acid (CAS 1368413-75-5)
- 1-(6-(tert-Butylamino)-4-methylpyridin-3-yl)propan-1-one (CAS 1355237-57-8)
- (2s)-2-Amino-N-(1-(o-tolyl)ethyl)butanamide (CAS 1372877-46-7)
- 3′,5′-Dibromo-4′-hydroxyacetophenone (CAS 2887-72-1)
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- (R)-2-(3-Fluorophenyl)pyrrolidine Hydrochloride (CAS 1364890-61-8)
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- Phytomenadione/Vitamin K1 Impurity 94 (CAS CATO-C4X-220794)
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- (±)-1-Bromo-2-ethyl-3-methyl-d3-butane-3,4,4,4-d4 (CAS 1219805-84-1)
- 1-(2-Methylpropyl)cyclopropan-1-amine hydrochloride (CAS 1255717-83-9)
- Acetyl Tetrapeptide-11 (CAS 928006-88-6)
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