Spebrutinib besylate, >98% (HPLC) CAS 1360053-81-1
| CAS No. | 1360053-81-1 |
| Molecular Formula | C22H22FN5O3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Spebrutinib besylate, >98% (HPLC) (CAS 1360053-81-1) is a high-purity analytical reference standard with the molecular formula C22H22FN5O3C6H6O3S and a molecular weight of 581.62 g/mol.
The molecular framework of Spebrutinib besylate, >98% (HPLC) (C22H22FN5O3C6H6O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H22FN5O3 C6H6O3S |
| Molecular Weight | 581.62 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Spebrutinib Standards
Recommended Standards
- 61704-30-1 6-(4-Chlorophenyl)pyridine-2-carbaldehyde DTXSID90494575 (CAS 61704-30-1)
- 1-(2-Hydroxyethyl)-6-((2-(4-methoxyphenyl)-2-oxoethyl)thio)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS 946333-00-2)
- 1-(1-Methylazetidin-3-yl)piperazine (CAS 864350-81-2)
- (R)-2-Amino-3-(quinolin-3-yl)propanoic acid (CAS 135213-89-7)
- Allyl (3'R)-3-bromo-2-oxo-[1,3'-bipyrrolidine]-1'-carboxylate (CAS 209468-19-9)
- 6-({2-chloro-5-[(dimethylamino)sulfonyl]benzoyl}amino)hexanoic acid (CAS 923810-89-3)
- 8-Chloro-3-(3-chlorobut-2-en-1-yl)-2-methylquinolin-4-ol (CAS 88655-00-9)
- Ethyl 2-amino-5-benzylthiophene-3-carboxylate (CAS 216686-60-1)
- 6-Bromo-8-fluoroquinoline (CAS 220513-46-2)
- Semaglutide impurity 229 (CAS CATO-C4X-2226229)
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