1-Chloro-3-(triphenylphosphoranylidene)-2-propanone CAS 13605-66-8
| CAS No. | 13605-66-8 |
| Molecular Formula | C21H18ClOP |
| Molecular Weight | 352.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, organophosphorus functionality, a hydroxyl group, an ether linkage, chlorine substitution, 1-Chloro-3-(triphenylphosphoranylidene)-2-propanone is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 352.79 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
1-Chloro-3-(triphenylphosphoranylidene)-2-propanone (CAS 13605-66-8), molecular formula C21H18ClOP and molecular weight 352.79 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Chloro-3-(triphenylphosphoranylidene)-2-propanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H18ClOP |
| Molecular Weight | 352.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Halogen Content | Cl-containing |
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Recommended Standards
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- H-Gly-Ala-Gly-OH (CAS 16422-05-2)
- 3-(2,3-Difluorophenyl)-2-oxopropanoic acid (CAS 1339728-97-0)
- Semaglutide impurity 29 (CAS 110990-08-4)
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