(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone CAS 1360705-96-9
| CAS No. | 1360705-96-9 |
| Molecular Formula | C22H20Cl2N4O4 |
| Molecular Weight | 475.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone (CAS 1360705-96-9), molecular formula C22H20Cl2N4O4 and molecular weight 475.32 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone (C22H20Cl2N4O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H20Cl2N4O4 |
| Molecular Weight | 475.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
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- CU3H37T766 99593-25-6 Rilmazafone Rilmazafone [INN] 5-((2-Aminoacetamido)methyl)-1-(4-chloro-2-(o-chlorobenzoyl)phenyl)-N,N-dimethyl-1H-1,2,4-triazole-3-carboxamide 1H-1,2,4-Triazole-3-carboxamide, 5-(((aminoacetyl)amino)methyl)-1-(4-chloro-2-(2-chlorobenzoyl)phenyl)-N,N-dimethyl- 1H-1,2,4-Triazole-3-carboxamide, 5-(((aminoacetyl)amino)methyl)-1-(4-chloro-2-(2-chlorobenzoyl)phenyl)-N,N-dimethyl-, monohydrochloride Rilmazafona [Spanish] Rilmazafonum [Latin] Rilmazafona Rilmazafonum UNII-CU3H37T766 (CAS 99593-25-6)
- Cenobamate impurity 10 (CAS CATO-C4X-241610)
- 1-(5-Chloro-1H-pyrrolo[3,2-b]pyridin-3-yl)ethan-1-one (CAS 1260384-24-4)
- 3-Amino-N-isopentylbenzamide (CAS 1016705-25-1)
- Sodium 4-(((tert-butoxycarbonyl)amino)methyl)picolinate (CAS 1185292-66-3)
- Paliperidone Impurity 104 (CAS CATO-C4X-1724104)
- 1-(5-Hydroxy-2-methylpyridin-4-yl)ethan-1-one (CAS 1256809-33-2)
- 1,4-Dimethoxy-2-(methoxymethyl)benzene (CAS 103441-37-8)
- Ethyl (3-cyano-4,6-dimethylpyridin-2-yl)glycinate (CAS 1053659-98-5)
- 2-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide (CAS 1775346-41-2)
- ethyl 2-amino-4-[(diethylamino)methyl]-5-[(methylamino)carbonyl]thiophene-3-carboxylate hydrobromide (CAS 1177292-85-1)
- Tau Peptide (275-305) (Repeat 2 Domain) trifluoroacetate salt (CAS 330456-25-2)
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